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全麻下扁桃体切除术后早期口服补液的安全性:一项前瞻性随机对照试验。

The safety of early administration of oral fluid following general anesthesia in children undergoing tonsillectomy: a prospective randomized controlled trial.

机构信息

Department of Liver Surgery, West China Hospital / West China School of Nursing, Sichuan University, No. 37, Guoxue Alley, Wuhou District, Chengdu, Sichuan, 610041, China.

West China School of Nursing / Operating Room of Anesthesia Surgery Center, West China Hospital, Sichuan University, No. 37, Guoxue Alley, Wuhou District, Chengdu, Sichuan, 610041, China.

出版信息

BMC Anesthesiol. 2021 Jan 11;21(1):13. doi: 10.1186/s12871-020-01230-4.

DOI:10.1186/s12871-020-01230-4
PMID:33430774
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7798214/
Abstract

BACKGROUND

The feasibility and safety of administrating a small amount of oral fluid to children in the early recovery period following tonsillectomy under general anesthesia to reduce the thirst and its associated restlessness remain unknown.

METHODS

This study was approved by the institutional ethics committee and adhered to the CONSORT guidelines. Pediatric patients undergoing tonsillectomy who met the inclusion and exclusion criteria of our study were randomized into the study and control groups. In the study group, patients were given a small amount of water instantly after recovering from general anesthesia, which included the recovery of the cough and deglutition reflex, and attaining grade V of muscle strength. The control group was given a small amount of water at 4 to 6 h after the operation. The incidence of nausea and vomiting and the degree of thirst relief were measured and compared between the two groups.

RESULTS

Three hundred patients were randomized into each group. There was no significant difference in the incidence of nausea and vomiting at 20 min after drinking water between the two groups (P > 0.05). The thirst score of children over 5 years old in the study group was significantly lower than that of the control group (P < 0.05).

CONCLUSION

Early administration of a small amount of oral fluid to children following tonsillectomy and recovering from general anesthesia is not only safe but also effective in reducing postoperative thirst.

TRIAL REGISTRATION

Current Controlled Trials ChiCTR1800020058 , 12-12-2018.

摘要

背景

在全身麻醉下扁桃体切除术后早期恢复期给儿童服用少量口服补液以减轻口渴和相关躁动的可行性和安全性尚不清楚。

方法

本研究经机构伦理委员会批准,并遵循 CONSORT 指南。符合本研究纳入和排除标准的行扁桃体切除术的儿科患者被随机分为研究组和对照组。在研究组中,患者在全身麻醉恢复后立即给予少量水,包括咳嗽和吞咽反射的恢复以及达到肌力 V 级。对照组在手术后 4 至 6 小时给予少量水。测量和比较两组之间恶心和呕吐的发生率以及口渴缓解程度。

结果

每组 300 例患者被随机分组。两组患者在饮水后 20 分钟恶心和呕吐的发生率无显著差异(P>0.05)。研究组 5 岁以上儿童的口渴评分明显低于对照组(P<0.05)。

结论

扁桃体切除术后和全身麻醉恢复后早期给予儿童少量口服补液不仅安全,而且有效减轻术后口渴。

试验注册

当前对照试验 ChiCTR1800020058,2018 年 12 月 12 日。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b29c/7798214/1265eda97ebe/12871_2020_1230_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b29c/7798214/1265eda97ebe/12871_2020_1230_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b29c/7798214/1265eda97ebe/12871_2020_1230_Fig1_HTML.jpg

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