Department of Cardiovascular Surgery, Icahn School of Medicine at Mount Sini, New York, NY.
Department of Cardiovascular Surgery, Icahn School of Medicine at Mount Sini, New York, NY.
J Thorac Cardiovasc Surg. 2021 Mar;161(3):937-946. doi: 10.1016/j.jtcvs.2020.12.022. Epub 2020 Dec 13.
The durability of mitral valve repair (MVr) is usually defined by the absence of recurrent significant mitral regurgitation. Postrepair mitral stenosis (MS) is a less frequent and less studied mode of failure of MVr. We analyzed our experience in patients who underwent reoperation for postrepair MS to characterize mechanisms resulting in MS and to summarize reoperative surgical strategies and mid-term outcomes.
Using a prospective database, we retrospectively analyzed data on 35 consecutive patients who underwent reoperation for symptomatic moderate to severe MS between January 1, 2011, and February 1, 2020.
The mean patient age was 61.4 ± 11.4 years, and 69% were female. The median annuloplasty ring size used at the initial repair was 28 mm (interquartile range, 26-30 mm). Additional repair techniques at the initial operation included leaflet resection in 12 patients (34%) and commissuroplasty or edge-to-edge repair in 6 patients (18%). At reoperation, the most common mechanism of MS was pannus ingrowth in 20 patients (57%), leaflet calcification in 12 (34%), commissural fusion in 5 (14%), and tunnel effect (functional MS) in 3 (9%). Twenty-two patients (63%) underwent valve replacement, and 13 (37%) underwent valve re-repair. In patients who underwent re-repair, annuloplasty revision was performed in all patients, with 6 patients (46%) converted from complete ring to band, 4 (11%) converted from ring to pericardial annuloplasty, 2 (6%) converted to no annuloplasty, and 1 (8%) with annuloplasty ring upsizing. There were no in-hospital or 1-year mortalities. Survival at the 5-year follow-up was 93.9%.
MS causing late failure of MVr is frequently associated with smaller ring sizes and inflammatory or calcific changes in the valve. Highly selected patients may be good candidates for mitral valve re-repair.
二尖瓣修复(MVr)的耐久性通常定义为没有复发性重度二尖瓣反流。修复后二尖瓣狭窄(MS)是 MVr 失败的一种不太常见且研究较少的模式。我们分析了因修复后 MS 而行再次手术的患者的经验,以明确导致 MS 的机制,并总结再次手术的外科策略和中期结果。
使用前瞻性数据库,我们回顾性分析了 2011 年 1 月 1 日至 2020 年 2 月 1 日期间因症状性中重度 MS 而行再次手术的 35 例连续患者的数据。
患者平均年龄为 61.4±11.4 岁,69%为女性。初次修复时使用的中位成形环大小为 28mm(四分位距,26-30mm)。初次手术时采用的其他修复技术包括 12 例(34%)瓣叶切除术和 6 例(18%)交界切开术或边缘对边缘修复术。再次手术时,MS 最常见的机制是 20 例(57%)瓣叶内的肉芽组织增生、12 例(34%)瓣叶钙化、5 例(14%)交界融合和 3 例(9%)隧道效应(功能性 MS)。22 例(63%)患者行瓣膜置换,13 例(37%)患者行瓣膜再次修复。再次修复的患者中,所有患者均行成形环修正术,其中 6 例(46%)由全环改为环带、4 例(11%)由环改为心包环成形术、2 例(6%)改为无环成形术、1 例(8%)环增大。无院内或 1 年死亡率。5 年随访时存活率为 93.9%。
导致 MVr 晚期失败的 MS 常与较小的环大小和瓣叶的炎症或钙化变化有关。高度选择的患者可能是二尖瓣再次修复的良好候选者。