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坦桑尼亚乞力马扎罗山的高原相关疾病:当地转诊中心的两年调查

Altitude-Related Disorders on Mount Kilimanjaro, Tanzania: Two-Year Survey in a Local Referral Center.

作者信息

Dekker Marieke C J, Mremi Alex, Kilonzo Kajiru G, Nyakunga Gissela, Sakita Francis, Mvungi Mark, Urasa Sarah J, Masenga Gileard, Howlett William P

机构信息

Department of Medicine, Kilimanjaro Christian Medical Center, Moshi Kilimanjaro, United Republic of Tanzania.

Department of Pathology, Moshi Kilimanjaro, United Republic of Tanzania.

出版信息

Wilderness Environ Med. 2021 Mar;32(1):36-40. doi: 10.1016/j.wem.2020.10.003. Epub 2021 Jan 9.

Abstract

INTRODUCTION

A significant number of climbers on Mount Kilimanjaro are affected by altitude-related disorders. The aim of this study was to determine the main causes of morbidity and mortality in a representative cohort of climbers based on local hospital records.

METHODS

We conducted a 2-y retrospective chart review of all patients presenting to the main referral hospital in the region after a climb on Mount Kilimanjaro, including all relevant records and referrals for postmortem studies.

RESULTS

We identified 62 climbers who presented to the hospital: 47 inpatients and 15 outpatients. Fifty-six presented with high altitude illness, which included acute mountain sickness (n=8; 14%), high altitude pulmonary edema (HAPE) (n=30; 54%), high altitude cerebral edema (HACE) (n=7; 12%), and combined HAPE/HACE (n=11; 20%). The mean altitude of symptom onset ranged from 4600±750 m for HAPE to 5000±430 m for HAPE/HACE. The vast majority of inpatients (n=41; 87%) were improved on discharge. Twenty-one deceased climbers, most having died while climbing (n=17; 81%), underwent postmortem evaluation. Causes of death were HAPE (n=16; 76%), HAPE/HACE (n=3; 14%), trauma (1), and cardiopulmonary (1).

CONCLUSIONS

HAPE was the main cause of death during climbing as well as for hospital admissions. The vast majority of climbers who presented to hospital made a full recovery.

摘要

引言

大量攀登乞力马扎罗山的登山者受到与海拔相关疾病的影响。本研究的目的是根据当地医院记录确定一组具有代表性的登山者发病和死亡的主要原因。

方法

我们对该地区主要转诊医院收治的所有攀登乞力马扎罗山后的患者进行了为期2年的回顾性病历审查,包括所有相关记录和尸检研究转诊。

结果

我们确定了62名到医院就诊的登山者:47名住院患者和15名门诊患者。56名患有高原病,包括急性高原病(n = 8;14%)、高原肺水肿(HAPE)(n = 30;54%)、高原脑水肿(HACE)(n = 7;12%)以及HAPE/HACE合并症(n = 11;20%)。症状出现的平均海拔高度范围为HAPE的4600±750米至HAPE/HACE的5000±430米。绝大多数住院患者(n = 41;87%)出院时病情好转。21名已故登山者,大多数在攀登过程中死亡(n = 17;81%),接受了尸检评估。死亡原因是HAPE(n = 16;76%)、HAPE/HACE(n = 3;14%)、创伤(1例)和心肺疾病(1例)。

结论

HAPE是攀登期间以及住院的主要死亡原因。到医院就诊的绝大多数登山者完全康复。

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