Gastroenterology, GB Pant Hospital, New Delhi, India.
Gastroenterology, GB Pant Hospital, New Delhi, India
BMJ Case Rep. 2021 Jan 11;14(1):e238363. doi: 10.1136/bcr-2020-238363.
Intraductal papillary mucinous neoplasms (IPMNs) are mucin-secreting cystic neoplasm of pancreas. They have a malignant potential. They are usually localised to the pancreas but occasionally can involve surrounding structures (1.9%-6.6%), like bile duct and duodenum, and are labelled as IPMN with invasion. Jaundice as a manifestation of IPMN is not common (4.5%). It can present as jaundice as a result of invasion of common bile duct (CBD) resulting in stricture formation or uncommonly as a result of fistulising to CBD with resultant obstruction of CBD by thick mucin secreted by this tumour. As only few cases (around 23) of mucin-filled CBD are reported in the literature. We are presenting our experience in dealing a rare case of obstructive jaundice caused by IPMN fistulising into CBD, highlighting the difficulties faced in managing such case, especially with regards to biliary drainage and what can be the optimum management in such cases.
导管内乳头状黏液性肿瘤(IPMNs)是胰腺的黏液分泌囊性肿瘤。它们具有恶性潜能。它们通常局限于胰腺,但偶尔也会累及周围结构(1.9%-6.6%),如胆管和十二指肠,并被标记为侵袭性 IPMN。黄疸作为 IPMN 的表现并不常见(4.5%)。它可因胆总管(CBD)受累导致狭窄形成而出现黄疸,也可因肿瘤分泌的厚黏液导致 CBD 瘘管形成而导致 CBD 阻塞而出现黄疸。由于文献中仅报道了约 23 例充满黏液的 CBD 病例。我们报告了处理罕见的由 IPMN 瘘管至 CBD 引起的阻塞性黄疸的经验,强调了处理此类病例的困难,特别是在胆道引流方面,以及在这种情况下的最佳管理方法。