Key Laboratory of Green Built Environment and Energy Efficient Technology, Beijing University of Technology, Beijing, China.
Indoor Air. 2021 Sep;31(5):1458-1472. doi: 10.1111/ina.12793. Epub 2021 Jan 12.
To investigate the need of allergic population for indoor environment quality, exposure effects of poor air quality on subjects with respiratory allergies were compared with those on healthy people, including perceptual responses, health symptoms, mental performance, and physiological responses. The experimental intervention was with and without ventilation at thermally neutral rooms, creating two exposure conditions indicated by CO concentration ranges of 502 to 3297 ppm (2438 ± 1527 ppm) and 517 to 5687 ppm (3615 ± 1527 ppm). 63 subjects (32 allergic subjects and 31 non-allergic subjects) were exposed to both conditions for 3 hours. The main results suggested that, compared with healthy people, people with respiratory allergy seem to be more sensitive or less acceptable to reduced air quality polluted by occupants during instantaneous exposure. Besides, the allergic group performed worse in cognitive tests than non-allergic group. After 3 hours of continuous exposure, people with respiratory allergy reported stronger intensity of respiratory irritations and seemed to suffer more inflammation indicated by a higher level of interleukin 1L-1β.
为了研究过敏人群对室内环境质量的需求,本研究比较了空气质量差对呼吸道过敏人群和健康人群的暴露影响,包括感知反应、健康症状、精神表现和生理反应。实验干预措施是在热中性房间内进行通风和不通风,创造了两种暴露条件,CO 浓度范围分别为 502 至 3297 ppm(2438 ± 1527 ppm)和 517 至 5687 ppm(3615 ± 1527 ppm)。63 名受试者(32 名过敏受试者和 31 名非过敏受试者)分别暴露于两种条件下 3 小时。主要结果表明,与健康人群相比,呼吸道过敏人群在瞬时暴露期间似乎对由居住者污染的空气质量较差更敏感或更难以接受。此外,过敏组在认知测试中的表现比非过敏组差。经过 3 小时的连续暴露后,呼吸道过敏人群报告呼吸刺激的强度更强,并且似乎遭受了更多的炎症,表现为白细胞介素 1L-1β水平更高。