Exploration of Kobayashi's aryne precursor: a potent reactive platform for the synthesis of polycyclic aromatic hydrocarbons.

Arynes due to their transient nature leads to remarkable and versatile applications in the synthetic world. Apparently, researchers have focused on the construction of simple to complex π-conjugated systems using arynes as the reactive platform. In this regard, Kobayashi's aryne precursor has shown a great extent of reactivity and afforded significant advancement in the synthesis of polycyclic aromatic systems with wide practical utility. This review emphasizes the extensive utilization of Kobayashi's aryne intermediates and their derivatives for the synthesis of different classes of polycyclic aromatic hydrocarbons (PAHs).