Department of Pathology, L.L.R.M Medical College, Meerut, Uttar Pradesh, India.
Department of Orthodontics, L.L.R.M Medical College, Meerut, Uttar Pradesh, India.
Indian J Pathol Microbiol. 2021 Jan-Mar;64(1):111-116. doi: 10.4103/IJPM.IJPM_628_20.
Till date, SARS CoV2 (COVID-19) is a pandemic viral infection in the world with the main and strong impact on respiratory airway, but this virus can affect any system of the human body.
This research is aimed to dictating the effect of SARS CoV2 infections on hematological, biochemical, and arterial blood gas parameters by using their mean values.
This retrospective study was included a total no. of 97 SARS CoV2 positive patients from 27 March to 15 May 2020. All positive patients were consented and took all the significant details.
We review the total 97 COVID-19 positive patients after obtaining all the hematological and other relevant clinical data from laboratory and medical records. The subjects were tabulated into three categories named; admitted (Gp A), discharged (Gp B), and expired (Gp C) patients and compared their hematological, biochemical parameters, and arterial blood gas analysis by using blood or serum and processed by proper methods.
The data was cleaned, edited, checked for completeness, and processed then entered in SPSS version 20 statistical software.
Blood samples were collected of all positive patients. Most of the patients had X-ray changes. Blood parameters showed that patients who were expired (Gp-C) suffered from anemia, lymphopenia, leucoytosis, neutrophilia, and thrombocytopenia with high ALT, pCO and low pO than admitted and expelled patients.
Result from this study provides that WBC count, absolute lymphocyte count, neutrophil count, and pO were independently associated and an important forecaster of mortality from SARS CoV2. All healthcare provides to regularly monitor above parameters indicators of COVID-19 infected patients to improve their quality of life and to reduce the risk of mortality rate.
迄今为止，SARS-CoV-2（COVID-19）是一种全球性的大流行病毒感染，主要和强烈影响呼吸道，但这种病毒可以影响人体的任何系统。
本研究旨在通过平均值来描述 SARS-CoV-2 感染对血液学、生化和动脉血气参数的影响。
这项回顾性研究共纳入了 2020 年 3 月 27 日至 5 月 15 日期间的 97 例 SARS-CoV-2 阳性患者。所有阳性患者均同意并提供了所有重要的详细信息。
我们回顾了从实验室和病历中获得所有血液学和其他相关临床数据的 97 例 COVID-19 阳性患者。将这些患者分为三组，分别为住院患者（Gp A）、出院患者（Gp B）和死亡患者（Gp C），并通过适当的方法比较他们的血液学、生化参数和动脉血气分析。
对数据进行清理、编辑、检查完整性并进行处理，然后输入到 SPSS 版本 20 统计软件中。
采集了所有阳性患者的血液样本。大多数患者有 X 光变化。血液参数显示，死亡患者（Gp-C）患有贫血、淋巴细胞减少、白细胞增多、中性粒细胞增多和血小板减少，同时 ALT、pCO 和 pO 降低，与住院和出院患者相比。
本研究结果表明，WBC 计数、绝对淋巴细胞计数、中性粒细胞计数和 pO 与死亡率独立相关，是 SARS-CoV-2 死亡率的重要预测指标。所有医疗保健提供者应定期监测 COVID-19 感染患者的上述参数指标，以提高他们的生活质量并降低死亡率。
