Department of Pathology, Northern Railway Central Hospital, New Delhi, India.
Indian J Pathol Microbiol. 2021 Jan-Mar;64(1):183-185. doi: 10.4103/IJPM.IJPM_341_19.
Primary cutaneous apocrine carcinomas are rare cutaneous adnexal neoplasm with less than 100 cases reported in the literature. The tumor arises in areas rich in apocrine glands particularly axilla, modified apocrine glands such as ceromucinous and Moll's glands. Most of these carcinomas are indolent and slowly growing but few rapidly progressive and extremely aggressive? cases have also been reported. Wide local excision with clear margins and sentinel lymph node biopsy is standard treatment of choice.This case was of much interest from the diagnostic point of view both microscopically as well as immunohistochemically. We report a case of 46-year-old man who presented to our hospital with an ulcerated painless nodular mass in his right axilla.With combined use of microscpic features, special stains and immunohistochemical examination the case was correctly diagnosed as primary cutaneous apocrine carcinoma.
原发性皮肤大汗腺癌是一种罕见的皮肤附属器肿瘤,文献中报道的病例少于 100 例。该肿瘤发生于大汗腺丰富的区域,特别是腋窝、改良大汗腺如皮脂膜和 Moll 腺。这些癌大多数为惰性和缓慢生长,但也有少数快速进展和极其侵袭性的病例报道。广泛局部切除加切缘清晰和前哨淋巴结活检是标准的治疗选择。该病例从显微镜下和免疫组织化学检查两方面来看都具有很大的诊断意义。我们报告了一例 46 岁男性,因右侧腋窝无痛性溃疡性结节就诊。通过显微镜下特征、特殊染色和免疫组织化学检查,该病例被正确诊断为原发性皮肤大汗腺癌。