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DAMPening Mortality in COVID-19: Therapeutic Insights From Basic Cardiometabolic Studies on S100A8/A9.

作者信息

Hanssen Nordin M J, Spaetgens Bart, Nagareddy Prabhakara R, Murphy Andrew J

机构信息

Diabetes Center, Department of Vascular and Internal Medicine, Amsterdam University Medical Center, Amsterdam, the Netherlands (N.M.J.H.).

Department of Internal Medicine, Division of General Internal Medicine, Section Geriatric Medicine, Maastricht University Medical Center, the Netherlands (B.S.).

出版信息

Circulation. 2021 Mar 9;143(10):971-973. doi: 10.1161/CIRCULATIONAHA.120.053025. Epub 2021 Jan 12.

DOI:10.1161/CIRCULATIONAHA.120.053025
PMID:33434052
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7940571/
Abstract
摘要

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Cell. 2020 Sep 17;182(6):1401-1418.e18. doi: 10.1016/j.cell.2020.08.002. Epub 2020 Aug 5.
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Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis.一过性间歇性高血糖通过促进髓系细胞生成加速动脉粥样硬化。
Circ Res. 2020 Sep 11;127(7):877-892. doi: 10.1161/CIRCRESAHA.120.316653. Epub 2020 Jun 22.
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Therapeutic Vaccine Against S100A9 (S100 Calcium-Binding Protein A9) Inhibits Thrombosis Without Increasing the Risk of Bleeding in Ischemic Stroke in Mice.
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Mech Ageing Dev. 2022 Jun;204:111667. doi: 10.1016/j.mad.2022.111667. Epub 2022 Mar 25.
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Hematopoietic progenitor cell liabilities and alarmins S100A8/A9-related inflammaging associate with frailty and predict poor cardiovascular outcomes in older adults.造血祖细胞负债和警报素 S100A8/A9 相关的炎症衰老与虚弱相关,并可预测老年人不良心血管结局。
Aging Cell. 2022 Mar;21(3):e13545. doi: 10.1111/acel.13545. Epub 2022 Feb 15.
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Circulating levels of calprotectin, a signature of neutrophil activation in prediction of severe respiratory failure in COVID-19 patients: a multicenter, prospective study (CalCov study).循环钙卫蛋白水平可预测 COVID-19 患者的严重呼吸衰竭:一项多中心前瞻性研究(CalCov 研究)
Inflamm Res. 2022 Jan;71(1):57-67. doi: 10.1007/s00011-021-01516-4. Epub 2021 Oct 30.
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Neutrophils in cardiovascular disease: warmongers, peacemakers, or both?中性粒细胞与心血管疾病:好战分子、和平缔造者,还是二者皆是?
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