Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China.
National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Int J Infect Dis. 2021 Mar;104:407-414. doi: 10.1016/j.ijid.2021.01.007. Epub 2021 Jan 9.
Zhejiang is a southeastern province of China with middle level notification rates of tuberculosis in China, but more than 27,000 pulmonary tuberculosis (PTB) cases are still reported annually in this province. We aimed to analyze the time trends of PTB cases and bacteriologically confirmed cases notification rates at the province and city levels of Zhejiang during 2005-2018.
Data from the web-based TB Information Management System of Zhejiang Province were used to calculate annual notification rates per 100,000 population of PTB cases and bacteriologically confirmed cases for Zhejiang Province and its 11 cities. The joinpoint regression method was used to analyze the time trends and calculate the annual percentage change of notification rates.
There were 480,668 notified PTB cases in Zhejiang Province during 2005-2018, 38.78% of which were bacteriologically confirmed cases. Both the PTB cases and bacteriologically confirmed cases notification rates of Zhejiang Province have declined since 2007. Most of the cities' time trends were the same as Zhejiang Province. The PTB cases and bacteriologically confirmed cases notification rates of males and elderly people are the highest in both sexes and among the four age groups, but the decline speeds of the two groups were slowest.
With the effective implementation of TB control measures and projects, the PTB cases notification rates of Zhejiang Province have declined. In order to reach the target in 2035 of the End TB Strategy, additional efforts should be made in the diagnosis and treatment of TB patients, particularly with regard to males and older adult people.
浙江是中国东南部的一个省份，其结核病报告发病率处于全国中等水平，但该省每年仍报告超过 27000 例肺结核（PTB）病例。我们旨在分析 2005-2018 年期间浙江省及其 11 个城市的肺结核病例和细菌学确诊病例报告率的时间趋势。
使用基于网络的浙江省结核病信息管理系统的数据，计算浙江省及其 11 个城市每年每 10 万人的肺结核病例和细菌学确诊病例的报告率。采用 Joinpoint 回归方法分析时间趋势并计算报告率的年变化百分比。
2005-2018 年期间，浙江省共报告了 480668 例肺结核病例，其中 38.78%为细菌学确诊病例。自 2007 年以来，浙江省的肺结核病例和细菌学确诊病例报告率均呈下降趋势。大多数城市的时间趋势与浙江省相同。男性和老年人的肺结核病例和细菌学确诊病例报告率在两性和四个年龄组中均最高，但这两个群体的下降速度最慢。
随着结核病控制措施和项目的有效实施，浙江省的肺结核病例报告率有所下降。为了实现 2035 年终结结核病战略的目标，应在结核病患者的诊断和治疗方面做出更多努力，特别是针对男性和老年人群。
