College of Pharmacy, Chongqing Medical University, Chongqing, 400016, China.
Forensic Identification Center, Chongqing Institution of Higher Learning Center of Forensic Science Engineering and Research, Southwest University of Political Science and Law, Chongqing, 401120, China.
Carbohydr Polym. 2021 Mar 1;255:117338. doi: 10.1016/j.carbpol.2020.117338. Epub 2020 Nov 2.
A magnetically and recyclable multifunctional nanohybrid adsorbent (IL-FeO@SiO@CS/GO) with chitosan, graphene oxide and ionic liquid was prepared by glutaraldehyde cross-linking reaction, acylation reaction and directly grafted method. The incorporation of CS, GO and IL could collaboratively enhance adsorption for 5 alkaloids. The Box-Benhnken design was applied to optimize the experimental parameters affecting the extraction efficiency. The adsorption kinetic was further used to describe the adsorption process, revealing alkaloids adsorption was a chemisorption process, which was well represented by pseudo-second-order model. Concerning the equilibrium behavior, the adsorption was multilayer and heterogeneous adsorption that satisfactorily modeled by the Freundlich model. Under optimal conditions, good adsorption capacity for morphine, codeine, ephedrine, amphetamine and benzoylecgonine (7.2, 8.4, 9.2, 5.8 and 11.2 mg g, respectively) were obtained via multiple mechanisms to attain simultaneous extraction of alkaloids. Accordingly, IL-FeO@SiO@CS/GO nanohybrid adsorbent could be extended as a potential adsorbent for extraction of illicit additives in food samples.
一种具有磁性和可回收功能的多功能纳米杂化吸附剂（IL-FeO@SiO@CS/GO），由戊二醛交联反应、酰化反应和直接接枝法制备而成，其中含有壳聚糖、氧化石墨烯和离子液体。CS、GO 和 IL 的掺入可以协同增强对 5 种生物碱的吸附。采用 Box-Benhnken 设计优化了影响萃取效率的实验参数。进一步采用吸附动力学来描述吸附过程，揭示出生物碱的吸附是一个化学吸附过程，该过程很好地符合准二级模型。关于平衡行为，吸附是多层和非均相吸附，通过 Freundlich 模型很好地模拟了吸附过程。在最佳条件下，通过多种机制获得了吗啡、可待因、麻黄碱、苯丙胺和苯甲酰古柯碱的良好吸附能力（分别为 7.2、8.4、9.2、5.8 和 11.2mg/g），从而实现了生物碱的同时提取。因此，IL-FeO@SiO@CS/GO 纳米杂化吸附剂可以作为一种潜在的吸附剂，用于从食品样品中提取非法添加剂。
