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原发性后房虹膜夹型人工晶状体植入术治疗人工晶状体脱位的长期手术效果。

Long-term surgical outcomes of primary retropupillary iris claw intraocular lens implantation for the treatment of intraocular lens dislocation.

机构信息

Department of Ophthalmology, Institute of Vision Research, Severance Eye Hospital, Yonsei University College of Medicine, 50-1, Yonseiro, Seodaemun-gu, Seoul, 03722, Korea.

Department of Ophthalmology, Institute of Vision Research, Gangnam Severance Hospital, Yonsei University College of Medicine, 211, Eonjuro, Gangnam-gu, Seoul, 06273, Korea.

出版信息

Sci Rep. 2021 Jan 12;11(1):726. doi: 10.1038/s41598-020-80292-3.

Abstract

We aimed to investigate the efficacy and safety of primary retropupillary iris claw intraocular lens (R-IOL) implantation in patients with complete intraocular lens (IOL) dislocation. In this single-center retrospective case series, we reviewed the medical records of patients who underwent R-IOL implantation surgery with pars plana vitrectomy for the treatment of IOL dislocation between September 2014 and July 2019. The primary outcome was change in visual acuity (VA) up to 24 months postoperatively. The secondary outcomes included changes in intraocular pressure (IOP), refractive errors, and endothelial cell count (ECC) over the same period. Data of 103 eyes (98 patients) were analyzed. The mean uncorrected VA was significantly improved at one month postoperatively (- 0.69 logMAR, P < 0.001), compared to the preoperative value. IOP (- 2.3 mmHg, P = 0.008) and ECC (- 333.4 cells/mm, P = 0.027) significantly decreased one month post-surgery and remained stable thereafter. Postoperative mean spherical equivalents were similar to the prediction error throughout the follow-up period. IOP elevation (n = 8, 7.8%), cystoid macular edema (n = 4, 3.9%), and dislocation of the R-IOL (n = 10, 9.7%) were managed successfully. Overall, primary R-IOL implantation with pars plana vitrectomy is effective and safe for correcting IOL dislocation due to various causes.

摘要

我们旨在研究原发性后房虹膜夹式人工晶状体(R-IOL)植入术治疗完全性人工晶状体(IOL)脱位的疗效和安全性。在这项单中心回顾性病例系列研究中,我们回顾了 2014 年 9 月至 2019 年 7 月期间因 IOL 脱位而行后房虹膜夹式 IOL 植入术联合玻璃体切除术治疗的患者的病历。主要结局是术后 24 个月时视力(VA)的变化。次要结局包括同一时期内眼内压(IOP)、屈光不正和内皮细胞计数(ECC)的变化。分析了 103 只眼(98 例)的数据。与术前相比,术后 1 个月时未矫正视力(VA)明显提高(-0.69 logMAR,P < 0.001)。术后 1 个月时 IOP(-2.3mmHg,P = 0.008)和 ECC(-333.4 个细胞/mm,P = 0.027)显著下降,此后保持稳定。术后平均球镜等效物在整个随访期间与预测误差相似。IOP 升高(n = 8,7.8%)、囊样黄斑水肿(n = 4,3.9%)和 R-IOL 脱位(n = 10,9.7%)经处理后均得到改善。总之,对于各种原因引起的 IOL 脱位,后房虹膜夹式 IOL 植入术联合玻璃体切除术是一种有效且安全的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23b8/7804091/c2314f973791/41598_2020_80292_Fig1_HTML.jpg

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