Raz S, Ehrlich R M, Zeidman E J, Alarcon A, McLaughlin S
Division of Urology, University of California, Los Angeles.
J Urol. 1988 Mar;139(3):524-7. doi: 10.1016/s0022-5347(17)42510-9.
Surgical therapy was required for 42 incontinent female patients with myelomeningocele who had urodynamically documented high pressure bladders. Conservative treatment consisting of cholinolytic and alpha-adrenergic agents, and intermittent self-catheterization had failed. The surgical approach consisted of perivesical denervation (for hyperreflexia), Burch bladder neck suspension, enlargement cystoplasty and ureteral reimplantation when required. Among 33 patients (79 per cent) there was no incontinence on intermittent self-catheterization and 6 (14 per cent) had improvement with rare urgency or stress incontinence. In 3 patients (7 per cent) sphincteric incompetence required a transvaginal sling procedure.
42例患有脊髓脊膜膨出且尿动力学检查显示膀胱高压的尿失禁女性患者需要接受手术治疗。包括使用胆碱能抑制剂和α-肾上腺素能药物以及间歇性自我导尿的保守治疗均告失败。手术方法包括膀胱周围去神经支配(用于治疗反射亢进)、伯奇膀胱颈悬吊术、扩大膀胱成形术以及必要时的输尿管再植术。33例患者(79%)在间歇性自我导尿时不再失禁,6例(14%)病情有所改善,仅有罕见的急迫性或压力性尿失禁。3例患者(7%)因括约肌功能不全需要行经阴道吊带手术。