Sarkis Julien, Nawfal Georges, El-Haddad Elias, Tayeh Georges Abi, Mahfoud Nathalie, Sarkis Pierre
Department of Urology, Hôtel-Dieu de France Hospital, Beirut, Lebanon.
Department of Radiology, Saint Joseph Hospital, Beirut, Lebanon.
Future Sci OA. 2020 Oct 20;7(2):FSO637. doi: 10.2144/fsoa-2020-0065.
Granulomatous prostatitis (GnP) is an interesting complication of bacillus Calmette-Guérin (BCG) therapy as it mimics prostate cancer on clinical, biochemical and imaging examinations. In the era of multiparametric prostate MRI (mpMRI), differentiation of GnP from prostate cancer on imaging is essential.
We report a case of post-BCG GnP in a patient with nonmuscle invasive bladder cancer, presenting with a prostate-specific antigen level of 21.6 ng/ml and prostate imaging reporting and data system (PI-RADS) 5 peripheral lesions. A mpMRI performed 6 months before showed a score 2 of PI-RADS.
The comparison of mpMRI images before and after BCG administration gives urologists, oncologists and radiologists a precise idea of the mpMRI changes that occur following BCG administration to eventually prevent unnecessary biopsies in future patients.
肉芽肿性前列腺炎(GnP)是卡介苗(BCG)治疗的一种有趣并发症,因为它在临床、生化和影像学检查中类似前列腺癌。在多参数前列腺MRI(mpMRI)时代,在影像学上鉴别GnP与前列腺癌至关重要。
我们报告一例非肌层浸润性膀胱癌患者卡介苗治疗后发生GnP的病例,其前列腺特异性抗原水平为21.6 ng/ml,前列腺影像报告和数据系统(PI-RADS)评分为5分的外周病变。6个月前进行的mpMRI显示PI-RADS评分为2分。
比较卡介苗给药前后的mpMRI图像,能让泌尿外科医生、肿瘤学家和放射科医生准确了解卡介苗给药后发生的mpMRI变化,最终避免未来患者进行不必要的活检。