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关于妊娠血小板减少症管理的 HOW 协作立场文件。

HOW Collaborative position paper on the management of thrombocytopenia in pregnancy.

机构信息

Liverpool Hospital, Sydney, New South Wales, Australia.

Royal Women's Hospital, Melbourne, Victoria, Australia.

出版信息

Aust N Z J Obstet Gynaecol. 2021 Apr;61(2):195-204. doi: 10.1111/ajo.13303. Epub 2021 Jan 12.

Abstract

Thrombocytopenia in pregnancy is a common occurrence, affecting up to 10% of women by the time of birth. These recommendations aim to provide pragmatic guidance on the investigation, diagnosis and management of thrombocytopenia in pregnancy; including safety of neuraxial anaesthesia and precautions required for birth. Management of neonatal thrombocytopenia is also addressed. The authors are clinicians representing haematology, obstetric medicine, maternal-fetal medicine, and anaesthesia. Each author conducted a detailed literature review then worked collaboratively to produce a series of unanimous recommendations. The recommendation strength is limited by the lack of high-quality clinical trial data, and represents level C evidence.

摘要

妊娠期间血小板减少症较为常见,高达 10%的孕妇会在分娩时发生这种情况。本指南旨在为妊娠期间血小板减少症的调查、诊断和管理提供实用指导,包括椎管内麻醉的安全性和分娩时的注意事项。还涉及新生儿血小板减少症的管理。作者是来自血液学、产科医学、母胎医学和麻醉学领域的临床医生。每位作者都进行了详细的文献复习,然后合作制定了一系列一致的建议。由于缺乏高质量的临床试验数据,本指南的推荐强度受到限制,属于 C 级证据。

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