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基于正念和接纳的干预措施对2型糖尿病患者糖尿病困扰和血糖水平的影响:系统评价与荟萃分析

Effects of mindfulness- and acceptance-based interventions on diabetes distress and glycaemic level in people with type 2 diabetes: Systematic review and meta-analysis.

作者信息

Ngan Hau Yi, Chong Yuen Yu, Chien Wai Tong

机构信息

The Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.

出版信息

Diabet Med. 2021 Apr;38(4):e14525. doi: 10.1111/dme.14525. Epub 2021 Feb 1.

Abstract

AIM

For people with type 2 diabetes, self management and fear of disease complication often cause psychological distress. Mindfulness and acceptance might be beneficial for reducing diabetes-related distress and glycaemic level. We systematically review the effects of mindfulness- and acceptance-based interventions on diabetes distress and glycaemic level in community-dwelling adults with type 2 diabetes.

METHODS

Seven electronic databases (English and Chinese) were searched comprehensively from inception to June 2020. Data extraction and methodological quality assessment were independently performed by two reviewers using Grading of Recommendations, Assessment, Development and Evaluations criteria.

RESULTS

Nine RCTs (801 participants) examining the effects of acceptance and commitment therapy, mindfulness-based cognitive therapy, mindfulness-based stress reduction and self-directed mindfulness practice were included. In the reviewed RCTs, the majority of participants (mean age: 50-66 years, average disease duration: 4-10 years) had suboptimal diabetes control (HbA >7.0%, 53 mmol/mol). Compared with controls, the interventions significantly reduced diabetes distress (standardised mean difference, SMD = -0.37, 95% confidence intervals, CI: -0.63, -0.12; p < 0.01) and HbA (mean difference, MD = -0.35, 95% CI: -0.67, -0.04; p = 0.03) up to 1-month post-intervention. However, the underpowered studies may have led to overestimation, the interventions for diabetes distress and HbA were heterogeneous.

CONCLUSIONS

Within evidenced-based diabetes education programmes, mindfulness- and acceptance-based approaches may reduce distress and HbA levels and promote self care in people with type 2 diabetes. Further controlled trials are recommended to examine the clinical effectiveness of such programmes for people with type 2 diabetes of diverse clinical, cultural and socio-demographic backgrounds.

摘要

目的

对于2型糖尿病患者,自我管理和对疾病并发症的恐惧常常会导致心理困扰。正念和接纳可能有助于减轻与糖尿病相关的困扰和血糖水平。我们系统回顾了基于正念和接纳的干预措施对社区居住的2型糖尿病成年人的糖尿病困扰和血糖水平的影响。

方法

全面检索了7个电子数据库(英文和中文),检索时间从建库至2020年6月。由两名 reviewers 使用推荐分级、评估、制定和评价标准独立进行数据提取和方法学质量评估。

结果

纳入了9项随机对照试验(801名参与者),这些试验考察了接纳与承诺疗法、基于正念的认知疗法、基于正念的减压疗法和自我指导的正念练习的效果。在纳入综述的随机对照试验中,大多数参与者(平均年龄:50 - 66岁,平均病程:4 - 10年)的糖尿病控制不佳(糖化血红蛋白>7.0%,53 mmol/mol)。与对照组相比,干预措施在干预后长达1个月时显著降低了糖尿病困扰(标准化均差,SMD = -0.37,95%置信区间,CI:-0.63,-0.12;p < 0.01)和糖化血红蛋白(均差,MD = -0.35,95% CI:-0.67,-0.04;p = 0.03)。然而, 样本量不足的研究可能导致了高估,针对糖尿病困扰和糖化血红蛋白的干预措施具有异质性。

结论

在循证糖尿病教育项目中,基于正念和接纳的方法可能会降低2型糖尿病患者的困扰和糖化血红蛋白水平,并促进自我护理。建议进一步开展对照试验,以检验此类项目对具有不同临床、文化和社会人口背景的2型糖尿病患者的临床效果。

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