绝经后妇女新冠病毒感染率和死亡率的变化。
Change in Covid-19 infection and mortality rates in postmenopausal women.
机构信息
Obstetrics and Gynecology Clinic, DINOGMI, IRCCS-Ospedale San Martino, Genoa, Italy.
出版信息
Menopause. 2021 Jan 11;28(5):573-575. doi: 10.1097/GME.0000000000001731.
OBJECTIVE
To evaluate whether the rates of COVID-19 infection and death in women versus men differ with age.
METHODS
From data provided by the Italian National Institute of Statistics, we calculated the respective proportions of women among COVID-infected versus noninfected populations and male versus female infection and death rates, stratifying the results into 10-year age groups.
RESULTS
The prevalence of COVID-19 infection was 3.6% higher in women than in the general population from 20 to 59 years of age, then decreased to -13.3% below that of the general population between 60 and 89 years of age. Death rates among infected women showed the opposite age-related trend. In infected women, the mortality rate was -77.4% lower than that of men aged 20 to 59 years. Between 60 and 89 years of age, the difference in women decreases to -34.5% below that of men.
CONCLUSIONS
Our results indicate opposing age-related trends among women in infection and death rates due to COVID-19. Further studies are needed to examine the contribution of the phases of the female reproductive cycle to the observed variations.
目的
评估 COVID-19 感染和死亡在女性与男性中的发生率是否随年龄而异。
方法
我们从意大利国家统计局提供的数据中，计算了 COVID-19 感染者中女性与非感染者、男性与女性的感染率和死亡率的比例，并按 10 岁年龄组分层分析了结果。
结果
在 20 至 59 岁年龄组，COVID-19 感染在女性中的流行率比一般人群高 3.6%，而在 60 至 89 岁年龄组则比一般人群低 13.3%。感染女性的死亡率则呈现相反的年龄相关趋势。在感染女性中，死亡率比 20 至 59 岁的男性低 77.4%。在 60 至 89 岁年龄组，女性死亡率比男性低 34.5%。
结论
我们的结果表明，COVID-19 感染和死亡在女性中的发生率存在相反的年龄相关趋势。需要进一步研究女性生殖周期各阶段对观察到的变异的贡献。
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