Klepper L Ia
Med Radiol (Mosk). 1988 Feb;33(2):23-8.
The paper is devoted to the development of a mathematical model for describing probabilities of occurrence of radiation complications on the skin (as well as in other normal organs and tissues) during its irradiation with homogeneous and inhomogeneous dose fields as a function of an irradiated skin area. The model naturally necessitates the isolation of an equivalent dose (an equidosimetric value) introduced by I. B. Keirim-Marcus which can be effectively used for comparison of homogeneous and inhomogeneous dose fields in normal organs and tissues. The development of mathematical models describing probabilities of occurrence of radiation complications in normal organs and tissues opens up new opportunities for improvement of methods of cancer radiotherapy design.
本文致力于开发一种数学模型，用于描述在皮肤（以及其他正常器官和组织）受到均匀和非均匀剂量场照射时，辐射并发症发生概率与受照皮肤面积之间的函数关系。该模型自然需要分离出由I. B. 凯里姆 - 马库斯引入的等效剂量（等剂量值），它可有效地用于比较正常器官和组织中的均匀和非均匀剂量场。描述正常器官和组织中辐射并发症发生概率的数学模型的开发为改进癌症放射治疗设计方法开辟了新的机会。
