Testicular feminization syndrome.

The testicular feminization syndrome occurs as a result of faculty genetic programming. This inherited condition causes an XY male embryo to develop into a person who has an XY karyotype and a female appearance. The described individual appears "female" at birth and is naturally socialized as a female. A testicular feminized "female" may seek routine health care at a primary health care center. Upon examination, certain identifying physical characteristics may be observed. Primary amenorrhea and infertility are inherent characteristics of the condition. This article describes the testicular feminization syndrome, its etiology/pathophysiology and both subjective and objective findings. Nursing interventions such as data collection, family tree charts, Barr body screening, education, referral and counseling are suggested. Nurse practitioners have the opportunity to identify suspected cases and direct those individuals toward appropriate treatment and discreet counseling. Counseling generally will emphasize that the TFS individual may consider herself female.