Suppr超能文献

增强社区药房中纳洛酮鼻喷雾剂可及性的药师咨询效果。

Impact of pharmacist counseling to enhance the accessibility of naloxone nasal spray to patients in a community pharmacy setting.

出版信息

J Am Pharm Assoc (2003). 2021 Jul-Aug;61(4S):S127-S134. doi: 10.1016/j.japh.2020.12.007. Epub 2021 Jan 10.

Abstract

BACKGROUND

The Centers for Disease Control and Prevention guidelines recommend naloxone for every high-dose opioid prescription; in 2018, only 1 naloxone prescription was dispensed for every 69 high-dose opioid prescriptions. In Virginia, strategies for creating awareness and availability include the REVIVE! training and the standing protocol for pharmacists to dispense naloxone.

OBJECTIVES

To evaluate if a proactive offer for counseling by pharmacists improves the percent change of patients who receive a prescription for naloxone nasal spray compared with the previous year's naloxone nasal spray fill history and to determine if the pharmacist's counseling affects a patient's confidence with opioid overdose and naloxone use.

METHODS

Prospective 4-month, interventional study in southwest Virginia conducted at 5 geographically similar large community chain pharmacies. A National Drug Code activity report within each store was used to identify patients, aged 18-64 years, filling opioid medication without naloxone. A pharmacist recommended naloxone to patients at the point of care. Patients accepting the recommendation for naloxone received pharmacist counseling from a standardized counseling script and by using a naloxone nasal spray demo kit. All eligible patients were provided a postintervention survey assessing their confidence with naloxone, if naloxone had been recommended before, and if they were picking up naloxone on the basis of the pharmacist's recommendation. Results were analyzed using univariate and bivariate analyses.

RESULTS

A total of 121 naloxone prescriptions were dispensed; an increase of 36% compared with the same period during the previous year. In total, 38 patients completed the postintervention survey. After receiving pharmacist counseling, patients indicated being very confident with administering naloxone correctly and for recognizing an opioid overdose, 73.9% and 65.2%, respectively. Of the patients who completed the survey, 60.5% received naloxone and accepted counseling from the pharmacist.

CONCLUSION

After pharmacist counseling, naloxone dispensing increased, and patients were confident with both administration and recognition.

摘要

背景

疾病控制与预防中心的指南建议每开出一张高剂量阿片类药物处方,同时开出一剂纳洛酮;而 2018 年,每开出 69 张高剂量阿片类药物处方,才会开出 1 剂纳洛酮。在弗吉尼亚州,为了提高意识和可及性,采取了多项策略,包括开展 REVIVE!培训和药剂师分发纳洛酮的常备方案。

目的

评估药剂师主动提供咨询服务是否会提高患者接受纳洛酮鼻喷雾剂处方的比例,与前一年的纳洛酮鼻喷雾剂配药记录相比,并确定药剂师的咨询是否会影响患者对阿片类药物过量和纳洛酮使用的信心。

方法

这是在弗吉尼亚州西南部的 5 家地理位置相似的大型社区连锁药店进行的为期 4 个月的前瞻性干预研究。在每个商店中,使用国家药品代码活动报告来识别年龄在 18-64 岁之间、正在服用阿片类药物但没有纳洛酮的患者。药剂师在护理点向患者推荐纳洛酮。接受纳洛酮推荐的患者会接受来自标准化咨询脚本和纳洛酮鼻喷雾剂演示工具包的药剂师咨询。所有符合条件的患者都收到一份干预后调查问卷,评估他们对纳洛酮的信心、之前是否被推荐过纳洛酮,以及是否基于药剂师的建议去领取纳洛酮。使用单变量和双变量分析对结果进行分析。

结果

共开出 121 张纳洛酮处方,比前一年同期增加了 36%。共有 38 名患者完成了干预后调查。接受药剂师咨询后,患者表示对正确给予纳洛酮和识别阿片类药物过量非常有信心,分别为 73.9%和 65.2%。在完成调查的患者中,60.5%的人接受了纳洛酮,并接受了药剂师的咨询。

结论

在药剂师咨询后,纳洛酮的配药量增加了,而且患者对给药和识别都很有信心。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验