Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine Kaohsiung, Kaohsiung City, Taiwan.
Department of Neurology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine Kaohsiung, Kaohsiung City, Taiwan.
Sci Rep. 2021 Jan 13;11(1):957. doi: 10.1038/s41598-020-79609-z.
Parkinson's disease (PD) is an incapacitating neurodegenerative disease. Patients with PD and their caregivers may have interactive effects on each other's psychological well-being. This study aimed to assess the dyadic dynamics of resilience, fatigue, and suicidal ideation on the depression severity of PD patients and their caregivers. In total, 175 PD patients and 175 caregivers were recruited at a medical center from August 2018 to May 2020. Structural equation modeling (SEM) was used to examine the actor/partner effects on the psychological well-being of both the PD patients and their caregivers. The most common psychiatric diagnoses of both the PD patients (28.6%) and their caregivers (11.4%) were depressive disorders. The PD patients' and their caregivers' fatigue, suicidal ideation, and lack of resilience were significantly associated with the severity of their depression, respectively. Interactive effects existed between psychological well-being of individuals with PD and their caregivers. Clinicians must be aware of, and manage, these contributing factors between PD patients and their caregivers in order to prevent them from worsening each other's depression.
帕金森病（PD）是一种使人丧失能力的神经退行性疾病。PD 患者及其照护者可能会相互影响彼此的心理健康。本研究旨在评估韧性、疲劳和自杀意念对 PD 患者及其照护者抑郁严重程度的双重影响。总共招募了 175 名 PD 患者和 175 名照护者，于 2018 年 8 月至 2020 年 5 月在一家医疗中心进行研究。结构方程模型（SEM）用于检验 PD 患者及其照护者心理幸福感的个体/伴侣效应。PD 患者（28.6%）和照护者（11.4%）最常见的精神科诊断是抑郁症。PD 患者及其照护者的疲劳、自杀意念和缺乏韧性分别与抑郁严重程度显著相关。PD 患者和他们的照护者的心理健康之间存在相互作用。临床医生必须意识到这些因素，并对 PD 患者及其照护者进行管理，以防止他们的抑郁状况相互恶化。
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