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单向和球形多孔β-磷酸三钙在胫骨高位开放楔形截骨术中的应用:病例系列

Use of unidirectional and spherical porous β-tricalcium phosphate in opening-wedge high tibial osteotomy: a case series.

作者信息

Kikuchi Naoya, Yoshioka Tomokazu, Taniguchi Yu, Kanamori Akihiro, Yamazaki Masashi

机构信息

Department of Orthopedic Surgery, Faculty of Medicine, University of Tsukuba, Japan.

Division of Regenerative Medicine for Musculoskeletal System, Faculty of Medicine, University of Tsukuba, Japan.

出版信息

J Rural Med. 2021 Jan;16(1):52-55. doi: 10.2185/jrm.2020-007. Epub 2021 Jan 5.

Abstract

Unidirectional porous β-tricalcium phosphate (UDPTCP) consists of a novel porous artificial bone that is structurally different from conventional artificial bone comprised of spherical porous β-tricalcium phosphate (SPTCP). We present our first four clinical cases of opening-wedge high tibial osteotomy (OWHTO) using UDPTCP and SPTCP together. The patients' mean age was 54.5 ± 5.9 years, and the mean observation period was 20.8 ± 2.8 months. In OWHTO, two wedge shaped pieces of UDPTCP and SPTCP were cut to fit the gap and implanted parallel to each other in the anterior and posterior parts, respectively. We evaluated the correction loss and bone remodeling for UDPTCP and SPTCP over time using radiography and computed tomography, and evaluated the clinical outcomes. There was no correction loss reported in any case, and early bone remodeling was observed with UDPTCP. All patients achieved satisfactory clinical results with no adverse events.

摘要

单向多孔β-磷酸三钙(UDPTCP)是一种新型多孔人工骨,其结构与由球形多孔β-磷酸三钙(SPTCP)组成的传统人工骨不同。我们展示了首例同时使用UDPTCP和SPTCP进行胫骨高位开口楔形截骨术(OWHTO)的4例临床病例。患者的平均年龄为54.5±5.9岁,平均观察期为20.8±2.8个月。在OWHTO中,将两片楔形的UDPTCP和SPTCP切割后以适应间隙,并分别在前部和后部彼此平行植入。我们使用X射线摄影和计算机断层扫描评估了UDPTCP和SPTCP随时间的矫正丢失和骨重塑情况,并评估了临床结果。所有病例均未报告有矫正丢失情况,并且观察到UDPTCP出现了早期骨重塑。所有患者均取得了满意的临床效果,且无不良事件发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e02d/7788303/b8cddea5db51/jrm-16-052-g001.jpg

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