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Platypnoea-orthodeoxia syndrome induced by short-term weight loss: a case series.

作者信息

Tamura Yudai, Sakamoto Tomohiro

机构信息

Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center, 5-3-1 Chikami Minami-ku, Kumamoto 861-4193, Japan.

出版信息

Eur Heart J Case Rep. 2020 Dec 12;4(6):1-6. doi: 10.1093/ehjcr/ytaa498. eCollection 2020 Dec.

DOI:10.1093/ehjcr/ytaa498
PMID:33442630
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7793163/
Abstract

BACKGROUND

Platypnoea-orthodeoxia syndrome (POS) is an uncommon condition characterized by dyspnoea and arterial desaturation in the standing or sitting position that improves in the supine position.

CASE SUMMARY

We report two cases of POS caused by an atrial septal defect (ASD) and a patent foramen ovale (PFO). Both cases reported a recent decrease in body weight of more than 10 kg in a short time period. Transoesophageal echocardiography (TOE) with agitated saline bubble study revealed and a large amount of contrast bubble through the ASD (Patient 1) or the PFO (Patient 2) from the right atrium to the left atrium in the sitting position. Both patients were diagnosed by the finding of positional dyspnoea and the results of TOE using agitated saline bubble contrast.

DISCUSSION

Taken together, their presentations suggest that weight loss in a short time period could be a pathogenic factor for POS.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff77/7793163/8590d697b747/ytaa498f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff77/7793163/da823093480c/ytaa498f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff77/7793163/f7e38ad7a68f/ytaa498f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff77/7793163/df4d2e25b23d/ytaa498f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff77/7793163/083531cbcbc6/ytaa498f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff77/7793163/8590d697b747/ytaa498f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff77/7793163/da823093480c/ytaa498f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff77/7793163/f7e38ad7a68f/ytaa498f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff77/7793163/df4d2e25b23d/ytaa498f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff77/7793163/083531cbcbc6/ytaa498f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff77/7793163/8590d697b747/ytaa498f5.jpg

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本文引用的文献

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Respir Med. 2017 Aug;129:31-38. doi: 10.1016/j.rmed.2017.05.016. Epub 2017 May 31.
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Percutaneous Intervention to Treat Platypnea-Orthodeoxia Syndrome: The Toronto Experience.经皮介入治疗固缩性低通气-直立性低氧血症综合征：多伦多经验。
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平卧呼吸-直立性低氧血症综合征：直立性呼吸困难及可能的病理生理基础。
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Cardiac platypnea-orthodeoxia syndrome: an often unrecognized malady.心脏平卧呼吸-直立性低氧血症综合征：一种常未被识别的病症。
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Platypnea-orthodeoxia syndrome: a rare complication after right pneumonectomy.低通气-低氧血症综合征：右全肺切除术后的一种罕见并发症。
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