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下颌不对称作为颞下颌关节紊乱病的一个可能病因:一项针对134例患者的前瞻性队列研究。

Mandibular asymmetry as a possible etiopathologic factor in temporomandibular disorder: a prospective cohort of 134 patients.

作者信息

Toh Aileen Qiu Jin, Chan Joshua Lue Hang, Leung Yiu Yan

机构信息

Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong, Hong Kong.

Oral and Maxillofacial Surgery, Prince Philip Dental Hospital, 34 Hospital Road, Hong Kong, Hong Kong.

出版信息

Clin Oral Investig. 2021 Jul;25(7):4445-4450. doi: 10.1007/s00784-020-03756-w. Epub 2021 Jan 13.

Abstract

OBJECTIVES

The present study aimed to investigate mandibular asymmetry as a possible etiopathologic factor in temporomandibular disorder (TMD).

MATERIALS AND METHODS

A prospective cross-sectional study of patients with dentofacial deformities seeking corrective orthognathic surgery was conducted. The pre-operative prevalence of TMD in patients with mandibular asymmetry and other dentofacial deformities was assessed using the Diagnostic Criteria for TMD (DC/TMD) Axis I protocol.

RESULTS

A total of 134 patients were recruited - 82 with mandibular asymmetry and 52 without. There was a significantly higher prevalence of TMD in those with mandibular asymmetry (67.1%; 95% CI 59 to 75%) compared to those without (40.4%; 95% CI 32 to 49%, p = 0.002). The overall pre-operative prevalence of TMD in this population of patients was 56.7% (95% CI 48 to 65%). Pain disorder only was present in 9.7%, TMJ disorder only in 29.9%, and both pain and TMJ disorders in 17.2%. The most prevalent type of TMD is disc displacement with reduction (77.6%), followed by myalgia (35.5%) and arthralgia (21.1%).

CONCLUSION

The prevalence of TMD in those with mandibular asymmetry was significantly higher than those without, suggesting that mandibular asymmetry could be a possible etiopathologic factor in TMD.

CLINICAL RELEVANCE

The significantly higher prevalence of temporomandibular disorder in those with mandibular asymmetry suggests that we need to be especially cognizant of this condition in our pre-operative, surgical, and post-operative management of this group of orthognathic patients.

摘要

目的

本研究旨在调查下颌不对称作为颞下颌关节紊乱病(TMD)可能的病因病理因素。

材料与方法

对寻求正颌外科矫正手术的牙颌面畸形患者进行了一项前瞻性横断面研究。使用颞下颌关节紊乱病诊断标准(DC/TMD)轴I方案评估下颌不对称和其他牙颌面畸形患者术前TMD的患病率。

结果

共招募了134例患者,其中82例有下颌不对称,52例无下颌不对称。下颌不对称患者的TMD患病率(67.1%;95%可信区间59%至75%)显著高于无下颌不对称患者(40.4%;95%可信区间32%至49%,p = 0.002)。该组患者术前TMD的总体患病率为56.7%(95%可信区间48%至65%)。仅疼痛障碍占9.7%,仅颞下颌关节紊乱占29.9%,疼痛和颞下颌关节紊乱均占17.2%。最常见的TMD类型是可复性盘移位(77.6%),其次是肌痛(35.5%)和关节痛(21.1%)。

结论

下颌不对称患者的TMD患病率显著高于无下颌不对称患者,提示下颌不对称可能是TMD的病因病理因素。

临床意义

下颌不对称患者颞下颌关节紊乱病的患病率显著更高,这表明在对这组正颌患者进行术前、手术和术后管理时,我们需要特别关注这种情况。

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