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T6 以上创伤性脊髓损伤的表现和治疗趋势:西班牙一家三级医院 20 年的经验。

Trends in the presentation and management of traumatic spinal cord lesions above T6: 20-Year experience in a tertiary-level hospital in Spain.

机构信息

Critical Care Unit, Hospital Universitario Lucus Augusti, Lugo, Spain.

Critical Care Unit, Complexo Hospitalario Universitario A Coruña, Instituto de Investigación Biomédica de A Coruña (INIBIC), A Coruña, Spain.

出版信息

J Spinal Cord Med. 2022 Sep;45(5):720-727. doi: 10.1080/10790268.2020.1851857. Epub 2021 Jan 14.

Abstract

OBJECTIVE

To analyze the changes in demographic and lesion characteristics of persons with acute traumatic spinal cord injury (ATSCI) above T6 over a period of 20 years, and to evaluate their impact on ICU resources use, length of stay and mortality.

DESIGN

Retrospective observational study.

SETTING

Intensive Care Unit (ICU) of the University Hospital Complex of A Coruña, Spain.

PARTICIPANTS

The study included 241 persons between 1998 and 2017 with an ATSCI above T6. For the purposes of the analysis, the overall study period was divided into three subperiods.

RESULTS

Both the mean age of the people with ATSCI (49 vs. 51 vs. 57 years; P = 0.046) and the Charlson Comorbidity Index were higher during the last subperiod (mean: 1.9 ± 2.2; P < 0.01). The most frequent cause of the injury was falls, whose percentage increased over the years. The most common classification in the American Spinal Injury Association Impairment scale was grade A. An increase in the score of the Acute Physiology and Chronic Health Evaluation (APACHE II) score was observed (median: 9 vs. 10 vs. 15; P < 0.01). The length of stay in the ICU has decreased significantly over the years (30 ± 19 vs. 22 ± 14 vs. 19 ± 13 days). No significant differences were found between the rates of ICU or in-hospital mortality recorded over the three subperiods.

CONCLUSIONS

Despite the progressive increase in the age, comorbidity, and APACHE II, the length of ICU stay decreased significantly, with no associated changes in the mortality rates.

摘要

目的

分析 20 年来 T6 以上急性创伤性脊髓损伤(ATSCI)患者的人口统计学和病变特征变化,并评估其对 ICU 资源利用、住院时间和死亡率的影响。

设计

回顾性观察性研究。

地点

西班牙拉科鲁尼亚大学医院综合重症监护病房(ICU)。

参与者

本研究纳入了 1998 年至 2017 年间 241 例 T6 以上 ATSCI 患者。为了进行分析,将整个研究期间分为三个亚期。

结果

ATSCI 患者的平均年龄(49 岁、51 岁、57 岁;P=0.046)和 Charlson 合并症指数在最后一个亚期更高(平均值:1.9±2.2;P<0.01)。损伤最常见的原因是跌倒,其百分比逐年增加。美国脊髓损伤协会损伤量表中最常见的分类是 A 级。急性生理学和慢性健康评估(APACHE II)评分升高(中位数:9 分、10 分、15 分;P<0.01)。ICU 住院时间明显缩短(30±19 天、22±14 天、19±13 天)。三个亚期记录的 ICU 或院内死亡率没有显著差异。

结论

尽管年龄、合并症和 APACHE II 逐渐增加,但 ICU 住院时间显著缩短,死亡率无变化。

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