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中国天津创伤性脊髓损伤的流行病学:对735例病例的18年回顾性研究。

Epidemiology of traumatic spinal cord injury in Tianjin, China: An 18-year retrospective study of 735 cases.

作者信息

Li Hai-Liang, Xu Hong, Li Yu-Lin, Sun Shi-Wei, Song Wen-Ye, Wu Qiang, Ai Jie, Sun Jing-Cheng, Ning Guang-Zhi, Feng Shi-Qing

机构信息

Department of Orthopedics, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.

出版信息

J Spinal Cord Med. 2019 Nov;42(6):778-785. doi: 10.1080/10790268.2017.1415418. Epub 2018 Jan 11.

Abstract

Hospital-based retrospective study To evaluate the pathogenetic features of traumatic spinal cord injury (TSCI) during 1999-2016 according to changed injury etiology with time, explore different characteristics of patients suffered a TSCI during 1999-2007 and 2008-2016 in Tianjin, China. Tianjin Medical University General Hospital In this study, the medical records of TSCI patients were obtained from Tianjin Medical University General Hospital (TMUGH) from 1st January 1999 to 31th December 2016. Variables were recorded, including age, gender occupation, etiology, the level of injury, America Spinal Injury Association (ASIA) impairment scale, the severity, concomitant injuries, death and its cause. To explore the differences in characteristics by etiology and by two periods, related statistical methods were used to calculate the correlation of some variables. Differences in etiology of TSCI during 1999-2016 were evaluated and differences in epidemiological characteristics were separately compared and analyzed between the 1999-2007 period and the 2008-2016 period. From 1999-2016, 831 TSCI cases were identified and 96 cases were excluded from analyses. The male-to-female ratio was 2.9:1 and the mean age was 49.7±15.2 years, which changed significantly between 1999-2007 (45.1±14.2) and 2008-2016 (51.6±15.2). Traffic accidents (45.8%) were the leading cause of TSCI during the 1999-2007 period, followed by low falls (30.7%). However, the opposite result was observed during the 2008-2016 period. Significant difference was observed compared with thoracic, lumbar and sacral levels, cervical level was the most commonly affected levels and the percentage decreased to a certain degree between 1999-2007 and 2008-2016 (from 84.4% to 68.9%). The proportions of ASIA grades A, B, C, and D were 20.5%, 10.3%, 23.3%, and 45.9%, respectively. The percentage of complete tetraplegia decreased from 22.9% in 1999-2007 to 13.2% in 2008-2016, and the percentage of incomplete paraplegia increased from 9.7% to 27.9%. According to the changes in the epidemiological characteristics of TSCI, relevant health service, laws and regulations, preventative strategies should be readjusted to follow up the changing situation and epidemiological characteristics of TSCI.

摘要

基于医院的回顾性研究 为根据创伤性脊髓损伤(TSCI)病因随时间的变化来评估1999 - 2016年期间TSCI的发病特征,探讨中国天津1999 - 2007年和2008 - 2016年期间遭受TSCI患者的不同特征。天津医科大学总医院 在本研究中,TSCI患者的病历资料取自天津医科大学总医院(TMUGH),时间跨度为1999年1月1日至2016年12月31日。记录了相关变量,包括年龄、性别、职业、病因、损伤平面、美国脊髓损伤协会(ASIA)损伤分级、严重程度、合并伤、死亡情况及其原因。为探究病因和两个时期的特征差异,采用相关统计方法计算一些变量的相关性。评估了1999 - 2016年期间TSCI病因的差异,并分别比较和分析了1999 - 2007年期间与2008 - 2016年期间的流行病学特征差异。1999 - 2016年期间,共确定831例TSCI病例,96例被排除在分析之外。男女比例为2.9:1,平均年龄为49.7±15.2岁,1999 - 2007年(45.1±14.2)与2008 - 2016年(51.6±15.2)之间有显著变化。交通事故(45.8%)是1999 - 2007年期间TSCI的主要原因,其次是低跌落伤(30.7%)。然而,在2008 - 2016年期间观察到相反的结果。与胸段、腰段和骶段平面相比,差异显著,颈段是最常受累平面,且1999 - 2007年至2008 - 2016年期间该比例有一定程度下降(从84.4%降至68.9%)。ASIA A、B、C和D级的比例分别为20.5%、10.3%、23.3%和45.9%。完全性四肢瘫的比例从1999 - 2007年的22.9%降至2008 - 2016年的13.2%,不完全性截瘫的比例从9.7%增至27.9%。根据TSCI流行病学特征的变化,应调整相关卫生服务、法律法规及预防策略,以跟进TSCI不断变化的情况和流行病学特征。

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