Sakmann P, Pirovino M, Bansky G, Lüthy R, Malinverni R, Zimmerli W, Hirschel B
Medizinische Universitätskliniken, Bern.
Schweiz Med Wochenschr. 1988 Jan 23;118(3):82-8.
Hepatic manifestations of acquired immunodeficiency syndrome (AIDS) were analyzed in 76 consecutive patients. Serological markers of hepatitis B were found in 84%. All instances of biopsy-proven chronic hepatitis were associated with delta infection. One patient with intestinal cryptosporidiosis had a severe cholestasis. In the majority of patients histological examination of the liver revealed non-specific alterations, but in several cases was diagnostic of mycobacterial disease. The study of liver disease in HIV-infected patients could lead to a better understanding of diseases such as chronic hepatitis B and sclerosing cholangitis.