Richter E, Wünsch P H, Richter J, Bohndorf W
Klinik für Strahlentherapie, Universität Würzburg.
Strahlenther Onkol. 1988 Feb;164(2):59-67.
Malignant nasopharyngeal tumors are rare, so that there are only few communications about treatment results in dependence on histological findings. The histological classification of malignant tumors, especially in case of malignant lymphomas, has changed considerably during the last few years. All histological preparations available from 157 patients treated by radiotherapy between 1960 and 1985 have been reassessed. Above all it was attempted to classify the formerly current diagnoses "retothelial sarcoma" and "lymphosarcoma" according to today's criteria and to assign to a histological type those tumors which could not be exactly classified hitherto. This proceeding has increased especially the group of malignant non Hodgkin's lymphomas from seven to 29 patients. The therapy results achieved after irradiation are presented in dependence on histological data and compared to the results communicated in literature. A certain stagnation is found for the last few years showing that an optimum of present therapy possibilities has been reached at the individual therapy centers.
恶性鼻咽肿瘤较为罕见，因此关于依据组织学检查结果的治疗效果的交流很少。在过去几年中，恶性肿瘤的组织学分类，尤其是恶性淋巴瘤的组织学分类发生了很大变化。对1960年至1985年间接受放射治疗的157例患者的所有可用组织学标本进行了重新评估。首先，试图根据当今的标准对以前常用的诊断“网状内皮肉瘤”和“淋巴肉瘤”进行分类，并将迄今无法准确分类的肿瘤归为一种组织学类型。这一过程尤其使恶性非霍奇金淋巴瘤患者组从7例增加到29例。根据组织学数据呈现放疗后的治疗效果，并与文献中报道的结果进行比较。发现过去几年有一定的停滞，表明各个治疗中心在当前治疗可能性方面已达到最佳状态。
