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[Preliminary study on immunological changes and clinical significance of decitabine treatment for relapsed acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation].

作者信息

Cao X H, Zhao X S, Chang Y J, Xu L P, Zhang X H, Wang Y, Liu K Y, Huang X J, Zhao X Y

机构信息

Peking University People's Hospital & Peking University Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, National Clinical Research Center for Blood Diseases, Beijing 100044, China.

出版信息

Zhonghua Xue Ye Xue Za Zhi. 2020 Dec 14;41(12):1035-1040. doi: 10.3760/cma.j.issn.0253-2727.2020.12.012.

DOI:10.3760/cma.j.issn.0253-2727.2020.12.012
PMID:33445853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7840555/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f9b/7840555/a21c905932a4/cjh-41-12-1035-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f9b/7840555/ab99e3accd54/cjh-41-12-1035-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f9b/7840555/d1f7bf643211/cjh-41-12-1035-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f9b/7840555/a21c905932a4/cjh-41-12-1035-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f9b/7840555/ab99e3accd54/cjh-41-12-1035-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f9b/7840555/d1f7bf643211/cjh-41-12-1035-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f9b/7840555/a21c905932a4/cjh-41-12-1035-g003.jpg

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本文引用的文献

1
The consensus on the monitoring, treatment, and prevention of leukemia relapse after allogeneic hematopoietic stem cell transplantation in China.中国异基因造血干细胞移植后白血病复发的监测、治疗和预防共识。
Cancer Lett. 2018 Dec 1;438:63-75. doi: 10.1016/j.canlet.2018.08.030. Epub 2018 Sep 11.
2
Reversal of T Cell Exhaustion by the First Donor Lymphocyte Infusion Is Associated with the Persistently Effective Antileukemic Responses in Patients with Relapsed AML after Allo-HSCT.异基因造血干细胞移植后复发 AML 患者中,第一供者淋巴细胞输注可逆转 T 细胞耗竭,并与持久有效的抗白血病反应相关。
Biol Blood Marrow Transplant. 2018 Jul;24(7):1350-1359. doi: 10.1016/j.bbmt.2018.03.030. Epub 2018 Apr 9.
3
Effect of the in vivo application of granulocyte colony-stimulating factor on NK cells in bone marrow and peripheral blood.
粒细胞集落刺激因子体内应用对骨髓和外周血 NK 细胞的影响。
J Cell Mol Med. 2018 Jun;22(6):3025-3034. doi: 10.1111/jcmm.13539. Epub 2018 Mar 25.
4
Decitabine enhances targeting of AML cells by CD34 progenitor-derived NK cells in NOD/SCID/IL2Rg mice.地西他滨增强 CD34 祖细胞衍生的 NK 细胞对 NOD/SCID/IL2Rg 小鼠中 AML 细胞的靶向作用。
Blood. 2018 Jan 11;131(2):202-214. doi: 10.1182/blood-2017-06-790204. Epub 2017 Nov 14.
5
NK cell dysfunction in chronic lymphocytic leukemia is associated with loss of the mature cells expressing inhibitory killer cell Ig-like receptors.慢性淋巴细胞白血病中的自然杀伤细胞功能障碍与表达抑制性杀伤细胞免疫球蛋白样受体的成熟细胞缺失有关。
Oncoimmunology. 2017 May 19;6(7):e1330235. doi: 10.1080/2162402X.2017.1330235. eCollection 2017.
6
Chemotherapy versus Hypomethylating Agents for the Treatment of Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndrome after Allogeneic Stem Cell Transplant.化疗与去甲基化药物治疗异基因造血干细胞移植后复发的急性髓系白血病和骨髓增生异常综合征的对比
Biol Blood Marrow Transplant. 2016 Jul;22(7):1324-1329. doi: 10.1016/j.bbmt.2016.03.023. Epub 2016 Mar 26.
7
Risk stratification-directed donor lymphocyte infusion could reduce relapse of standard-risk acute leukemia patients after allogeneic hematopoietic stem cell transplantation.风险分层指导下的供者淋巴细胞输注可降低异基因造血干细胞移植后标准风险急性白血病患者的复发率。
Blood. 2012 Apr 5;119(14):3256-62. doi: 10.1182/blood-2011-09-380386. Epub 2012 Feb 14.
8
Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML).阿扎胞苷可增强急性髓系白血病(AML)患者异基因干细胞移植后调节性 T 细胞的扩增。
Blood. 2012 Apr 5;119(14):3361-9. doi: 10.1182/blood-2011-09-377044. Epub 2012 Jan 10.
9
Azacitidine for treatment of imminent relapse in MDS or AML patients after allogeneic HSCT: results of the RELAZA trial.阿扎胞苷治疗异基因造血干细胞移植后 MDS 或 AML 患者即将复发:RELAZA 试验结果。
Leukemia. 2012 Mar;26(3):381-9. doi: 10.1038/leu.2011.234. Epub 2011 Sep 2.
10
Wilms' tumor gene 1 expression: an independent acute leukemia prognostic indicator following allogeneic hematopoietic SCT.Wilms 瘤基因 1 表达:异基因造血干细胞移植后急性白血病的独立预后指标。
Bone Marrow Transplant. 2012 Apr;47(4):499-507. doi: 10.1038/bmt.2011.121. Epub 2011 Jun 6.