• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
[Acute myeloid leukemia with FIP1L1-PDGFRA fusion gene treated with imatinib: a case report and literature review].[伊马替尼治疗伴有FIP1L1-PDGFRA融合基因的急性髓系白血病：1例报告并文献复习]
Zhonghua Xue Ye Xue Za Zhi. 2020 Dec 14;41(12):1044-1046. doi: 10.3760/cma.j.issn.0253-2727.2020.12.014.
2
Discovery of imatinib-responsive FIP1L1-PDGFRA mutation during refractory acute myeloid leukemia transformation of chronic myelomonocytic leukemia.慢性粒单核细胞白血病转化为难治性急性髓系白血病时发现伊马替尼反应性 FIP1L1-PDGFRA 突变。
J Hematol Oncol. 2014 Mar 27;7:26. doi: 10.1186/1756-8722-7-26.
3
Maintenance therapy with imatinib appears necessary despite molecular remission in FIP1L1-PDGFRA fusion gene positive hypereosinophilic disorder.尽管FIP1L1-PDGFRA融合基因阳性的高嗜酸性粒细胞增多症患者已达到分子缓解，但伊马替尼维持治疗似乎仍有必要。
Leuk Res. 2008 Jan;32(1):169-71. doi: 10.1016/j.leukres.2007.04.004. Epub 2007 Jun 4.
4
Progressive multifocal leukoencephalopathy responsive to withdrawal of imatinib in a patient with FIP1L1-PDGFRA positive myeloid neoplasm.一名FIP1L1-PDGFRA阳性髓系肿瘤患者停用伊马替尼后病情缓解的进行性多灶性白质脑病
Leuk Lymphoma. 2020 Sep;61(9):2226-2229. doi: 10.1080/10428194.2020.1759052. Epub 2020 May 4.
5
A novel FIP1L1-PDGFRA mutant destabilizing the inactive conformation of the kinase domain in chronic eosinophilic leukemia/hypereosinophilic syndrome.一种新型FIP1L1-PDGFRA突变体，可破坏慢性嗜酸性粒细胞白血病/高嗜酸性粒细胞综合征中激酶结构域的非活性构象。
Allergy. 2009 Jun;64(6):913-8. doi: 10.1111/j.1398-9995.2009.01943.x. Epub 2009 Feb 7.
6
Detection of FIP1L1-PDGFRA fusion by FISH.通过荧光原位杂交检测FIP1L1-PDGFRA融合基因。
Br J Haematol. 2007 Aug;138(3):279. doi: 10.1111/j.1365-2141.2007.06637.x. Epub 2007 Jun 3.
7
Cessation of imatinib mesylate may lead to sustained hematologic and molecular remission in FIP1L1-PDGFRA-mutated hypereosinophilic syndrome.甲磺酸伊马替尼的停药可能导致FIP1L1-PDGFRA突变的嗜酸性粒细胞增多综合征出现持续的血液学和分子学缓解。
Am J Hematol. 2014 Jan;89(1):115. doi: 10.1002/ajh.23588. Epub 2013 Oct 15.
8
Imatinib discontinuation for hypereosinophilic syndrome harboring the FIP1L1-PDGFRA transcript.因携带FIP1L1-PDGFRA转录本的嗜酸性粒细胞增多综合征而停用伊马替尼。
Leuk Lymphoma. 2016;57(3):708-10. doi: 10.3109/10428194.2015.1065983. Epub 2015 Oct 2.
9
Hes1 upregulation contributes to the development of FIP1L1-PDGRA-positive leukemia in blast crisis.Hes1 的上调导致了 FIP1L1-PDGRA 阳性白血病在急变期的发展。
Exp Hematol. 2014 May;42(5):369-379.e3. doi: 10.1016/j.exphem.2014.01.009. Epub 2014 Jan 31.
10
Rapid reversion of eosinophilic gastroenteritis associated with FIP1L1-PDGFRA fusion after targeted therapy with imatinib.伊马替尼靶向治疗后，与FIP1L1-PDGFRA融合相关的嗜酸性粒细胞性胃肠炎迅速逆转。
Br J Haematol. 2006 Jan;132(2):123. doi: 10.1111/j.1365-2141.2005.05698.x.

本文引用的文献

1
Imatinib for the treatment of hypereosinophilic syndromes.伊马替尼治疗高嗜酸性粒细胞综合征。
Expert Rev Clin Immunol. 2018 Feb;14(2):163-170. doi: 10.1080/1744666X.2018.1425142. Epub 2018 Jan 9.
2
Presence of Additional Cytogenetic Abnormality of t(1;15) at Diagnosis of Chronic Myelogenous Leukemia-Chronic Phase.慢性髓性白血病慢性期诊断时伴额外细胞遗传学异常t(1;15)的存在
Ann Clin Lab Sci. 2016 May;46(3):308-11.
3
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.2016 年版世界卫生组织髓系肿瘤和急性白血病分类。
Blood. 2016 May 19;127(20):2391-405. doi: 10.1182/blood-2016-03-643544. Epub 2016 Apr 11.
4
Diagnostic challenges in the work up of hypereosinophilia: pitfalls in bone marrow core biopsy interpretation.嗜酸性粒细胞增多症检查中的诊断挑战：骨髓核心活检解读中的陷阱
Ann Hematol. 2016 Mar;95(4):557-62. doi: 10.1007/s00277-016-2598-x. Epub 2016 Jan 22.
5
Hypereosinophilic Syndrome.高嗜酸性粒细胞综合征
Clin Rev Allergy Immunol. 2016 Apr;50(2):240-51. doi: 10.1007/s12016-015-8506-7.
6
How I treat hypereosinophilic syndromes.我如何治疗高嗜酸性粒细胞综合征。
Blood. 2015 Aug 27;126(9):1069-77. doi: 10.1182/blood-2014-11-551614. Epub 2015 May 11.
7
Long-term follow-up of treatment with imatinib in eosinophilia-associated myeloid/lymphoid neoplasms with PDGFR rearrangements in blast phase.伊马替尼治疗处于急变期的伴有血小板衍生生长因子受体（PDGFR）重排的嗜酸性粒细胞增多相关髓系/淋系肿瘤的长期随访
Leukemia. 2013 Nov;27(11):2254-6. doi: 10.1038/leu.2013.129. Epub 2013 Apr 25.
8
Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes.当代关于嗜酸性粒细胞疾病和相关综合征的标准和分类的共识建议。
J Allergy Clin Immunol. 2012 Sep;130(3):607-612.e9. doi: 10.1016/j.jaci.2012.02.019. Epub 2012 Mar 28.
9
Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy.嗜酸性粒细胞增多综合征：一项多中心回顾性分析临床特征和治疗反应。
J Allergy Clin Immunol. 2009 Dec;124(6):1319-25.e3. doi: 10.1016/j.jaci.2009.09.022.
10
Recurrent finding of the FIP1L1-PDGFRA fusion gene in eosinophilia-associated acute myeloid leukemia and lymphoblastic T-cell lymphoma.嗜酸性粒细胞增多相关急性髓系白血病和T细胞淋巴细胞淋巴瘤中FIP1L1-PDGFRA融合基因的反复发现。
Leukemia. 2007 Jun;21(6):1183-8. doi: 10.1038/sj.leu.2404662. Epub 2007 Mar 22.

[Acute myeloid leukemia with FIP1L1-PDGFRA fusion gene treated with imatinib: a case report and literature review].

作者信息

Fan J C, You W W, Liu H X, Cai Y, Du X, Wang J X

机构信息

Department of Hematology, Shenzhen Second People's Hospital, The Affiliated Hospital of Shenzhen University, Shenzhen 518035, China.

Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China.

出版信息

Zhonghua Xue Ye Xue Za Zhi. 2020 Dec 14;41(12):1044-1046. doi: 10.3760/cma.j.issn.0253-2727.2020.12.014.

DOI:10.3760/cma.j.issn.0253-2727.2020.12.014
PMID:33445855
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7840551/
Abstract
摘要