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罕见的原发性肺原始神经外胚层肿瘤:一例报告及文献复习

Rare Primary Pulmonary Primitive Neuroectodermal Tumor: A Case Report and Literature Review.

作者信息

Wang Ning, Dong Shuang-Shuang, Wu Chun-Lin, Wang Ying, Meng Lian, Ren Yan, Cui Xiao-Bin, Li Man, Qi Yan

机构信息

Department of Pathology, Shihezi University School of Medicine, The First Affiliated Hospital to Shihezi University School of Medicine, Shihezi, Xinjiang 832002, People's Republic of China.

Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, Shihezi University, Shihezi, Xinjiang 832002, People's Republic of China.

出版信息

Onco Targets Ther. 2021 Jan 8;14:139-144. doi: 10.2147/OTT.S283967. eCollection 2021.

DOI:10.2147/OTT.S283967
PMID:33447055
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7802914/
Abstract

Primitive neuroectodermal tumors (PNETs) arising from the lung without thoracic wall involvement are extremely rare and particularly aggressive neoplasms. Herein, we present the case of a 41-year-old woman with pulmonary PNET diagnosed following histopathological, immunohistochemical, and molecular pathological examination of a surgical biopsy specimen. The case report is accompanied by a literature review of primary pulmonary PNETs.

摘要

起源于肺部且未累及胸壁的原始神经外胚层肿瘤(PNETs)极为罕见,是侵袭性很强的肿瘤。在此,我们报告一例41岁女性的肺部PNET病例,该病例经手术活检标本的组织病理学、免疫组织化学及分子病理学检查确诊。本病例报告还伴有对原发性肺部PNETs的文献综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92db/7802914/e6510de471ce/OTT-14-139-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92db/7802914/9e5f19f9fea1/OTT-14-139-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92db/7802914/e6510de471ce/OTT-14-139-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92db/7802914/9e5f19f9fea1/OTT-14-139-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92db/7802914/e6510de471ce/OTT-14-139-g0002.jpg

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World J Clin Cases. 2019 Feb 6;7(3):340-346. doi: 10.12998/wjcc.v7.i3.340.
2
Antiangiogenic therapy for primitive neuroectodermal tumor with thalidomide: A case report and review of literature.沙利度胺用于原始神经外胚层肿瘤的抗血管生成治疗:一例报告及文献综述
Medicine (Baltimore). 2017 Dec;96(51):e9272. doi: 10.1097/MD.0000000000009272.
3
Late onset of primary pulmonary primitive neuroectodermal tumor: a case report.
成人中罕见的对放疗敏感的原始神经外胚层肿瘤伴基因扩增:病例报告及文献复习。
J Int Med Res. 2022 Aug;50(8):3000605221118704. doi: 10.1177/03000605221118704.
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4
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J Clin Diagn Res. 2016 Nov;10(11):ED01-ED02. doi: 10.7860/JCDR/2016/19709.8839. Epub 2016 Nov 1.
5
Benefit of Sunitinib in the treatment of pulmonary primitive neuroectodermal tumors: a case report and literature review.舒尼替尼治疗肺原发性神经外胚层肿瘤的疗效:一例报告及文献复习
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