Stimac Dinko, Jankovic Dragan, Peric Ljiljana, Anic Kata, Nimsky Christopher
Neurosurgery, Health center of Primorje - Gorski Kotar county, Rijeka, HRV.
Neurosurgery, University Medical Centre of the Johannes Gutenberg University of Mainz, Mainz, DEU.
Cureus. 2020 Dec 13;12(12):e12058. doi: 10.7759/cureus.12058.
We describe a case of 49-years old female with a medical history of penicillin allergy, who suffered from brain infection caused by . Therefore, the available therapy was metronidazole, ceftriaxone, and chloramphenicol. Due to a deterioration of the general and neurological condition of the patient, it was decided to perform a scratch skin test on penicillin, which was negative. After that, penicillin was administrated parenterally. The patient showed no hypersensitive reaction. Improvement was achieved. The patient underwent three subsequent surgeries due to primary and recurrent brain abscesses. There was a distinct improvement in her clinical status. Two months after the second re-surgery, the control computed tomography showed complete regression of the abscess. Brain abscess caused by an is very resistant to medication. However, surgical evacuation significantly accelerates the healing process. A good medication therapy is crucial and in most cases the drug of choice is penicillin. We emphasize the importance of a combined approach for treating this unusual brain infection.
我们描述了一例49岁有青霉素过敏病史的女性患者，她患有由……引起的脑部感染。因此，可用的治疗药物是甲硝唑、头孢曲松和氯霉素。由于患者的一般状况和神经状况恶化，决定对青霉素进行皮肤划痕试验，结果为阴性。此后，对患者进行了青霉素非肠道给药。患者未出现过敏反应。病情有所改善。由于原发性和复发性脑脓肿，该患者随后接受了三次手术。其临床状况有明显改善。第二次再次手术后两个月，计算机断层扫描复查显示脓肿完全消退。由……引起的脑脓肿对药物治疗非常耐药。然而，手术引流可显著加速愈合过程。良好的药物治疗至关重要，在大多数情况下，首选药物是青霉素。我们强调采用联合方法治疗这种不寻常的脑部感染的重要性。
