高血压患者血浆醛固酮浓度升高与左心房管道功能之间的关联
Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension.
作者信息
Zhang Shenglin, Gao Xin, Wang Dongxia, Jiang Yinong, Liu Yan
机构信息
Department of General Surgery, The 1st Affiliated Hospital of Dalian Medical University, Zhongshan Road No. 222, Xigang District, Dalian, Liaoning, China.
Department of Cardiology, The 1st Affiliated Hospital of Dalian Medical University, Lianhe Road, No. 193, Shahekou District, Dalian, Liaoning, China.
出版信息
Int J Cardiol Hypertens. 2019 Jul 2;2:100015. doi: 10.1016/j.ijchy.2019.100015. eCollection 2019 Aug.
Aldosterone affects myocardial fibrosis and remodeling. The aim was to investigate the relationship between plasma aldosterone concentration (PAC) and left atrial (LA) function in hypertension. 148 hypertensive patients were studied. LA phasic function was evaluated by strain and strain rate imaging. Patients were divided into two groups based on PAC. LA early diastolic strain and strain rate (LA and LA) were lower in group II compared with group I ( < 0.05). Multivariate regression analysis showed that LA was independently related to PAC (β = -0.581, < 0.001). In conclusion, PAC is associated with LA conduit function in hypertension.
醛固酮影响心肌纤维化和重塑。目的是研究高血压患者血浆醛固酮浓度（PAC）与左心房（LA）功能之间的关系。对148例高血压患者进行了研究。通过应变和应变率成像评估LA的阶段性功能。根据PAC将患者分为两组。与第一组相比，第二组的LA舒张早期应变和应变率（LA和LA）较低（P<0.05）。多变量回归分析显示，LA与PAC独立相关（β=-0.581，P<0.001）。总之，在高血压患者中，PAC与LA的管道功能相关。
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