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美国2017 - 2018年高血压的患病率和控制率。

Prevalence and control rates of hypertension in the USA: 2017-2018.

作者信息

Chobufo Muchi Ditah, Gayam Vijay, Soluny Jean, Rahman Ebad U, Enoru Sostanie, Foryoung Joyce Bei, Agbor Valirie N, Dufresne Alix, Nfor Tonga

机构信息

Department of Medicine, Interfaith Medical Center, Brooklyn, NY, USA.

Department of Internal Medicine, St. Mary's Medical Center, Huntington, WV, USA.

出版信息

Int J Cardiol Hypertens. 2020 Jul 31;6:100044. doi: 10.1016/j.ijchy.2020.100044. eCollection 2020 Sep.

Abstract

BACKGROUND

Recent review of hypertension guidelines requires fresh updates of prevalence and control rates. Though retrospective analysis provided burden estimates, control rates were grossly misleading. We set out to update the prevalence and control rates of hypertension in the USA using contemporary NHANES data.

METHODS

Persons with mean systolic blood pressure (mSBP) ≥130 mmHg or mean diastolic blood pressure (mDBP) ≥80 mmHg or self-reported current use of antihypertensive medications were classified as hypertensives. Hypertensives on medications with mSBP <130 mmHg and mDBP <80 mmHg were classified as having well-controlled hypertension. Subgroup comparisons of hypertension prevalence were computed using Chi-square test. Predictors of hypertension and well-controlled BP were assessed using multivariable logistic regressions. Two tailed p-values <0.05 were considered statistically significant.

RESULTS

The prevalence of hypertension in the USA in 2017-2018 was 49.64% (95% CI 46.67-52.61) corresponding to 115(95% CI 104-128) million persons. NH Blacks: 58.53% (95% CI 55.39-61.60); Men: 54.46% (95% CI 51.01-57.87); older persons and obese individuals: 61.03% (95% CI 57.31-64.63) as well as persons with diabetes and CKD, comparatively. The overall rate of well-controlled hypertension was 39.64% (95% CI 36.20-42.81). Persons with at least a college degree: OR 2.20(95% CI 1.02-5.04, p=0.049) and persons with incomes ≥3 times the poverty threshold; OR 1.88(95% CI 1.1.8-2.99, p=0.011) had higher rates of well-controlled hypertension when compared to lowest categories.

CONCLUSION

One in every two persons ≥20 years in the USA has hypertension with only 39.64% on medications having well-controlled hypertension. Significant discrepancies exist in the burden and control rates in different subpopulation categories. Targeted interventions could help improve the prevalence and hypertension control rates in the USA.

摘要

背景

近期对高血压指南的回顾要求更新患病率和控制率。尽管回顾性分析提供了负担估计,但控制率极具误导性。我们着手利用当代美国国家健康与营养检查调查(NHANES)数据来更新美国高血压的患病率和控制率。

方法

平均收缩压(mSBP)≥130 mmHg或平均舒张压(mDBP)≥80 mmHg或自我报告当前正在使用抗高血压药物的人被归类为高血压患者。服用药物且mSBP<130 mmHg和mDBP<80 mmHg的高血压患者被归类为高血压得到良好控制。使用卡方检验计算高血压患病率的亚组比较。使用多变量逻辑回归评估高血压和血压控制良好的预测因素。双侧p值<0.05被认为具有统计学意义。

结果

2017 - 2018年美国高血压患病率为49.64%(95%置信区间46.67 - 52.61),相当于1.15亿(95%置信区间1.04 - 1.28亿)人。非裔美国人:58.53%(95%置信区间55.39 - 61.60);男性:54.46%(95%置信区间51.01 - 57.87);老年人和肥胖个体:61.03%(95%置信区间57.31 - 64.63),以及糖尿病和慢性肾脏病患者相对较高。高血压总体控制率为39.64%(95%置信区间36.20 - 42.81)。至少拥有大学学位的人:比值比(OR)为2.20(95%置信区间1.02 - 5.04,p = 0.049),收入≥贫困线3倍的人:OR为1.88(95%置信区间1.18 - 2.99,p = 0.011),与最低类别相比,其高血压控制良好率更高。

结论

在美国,每两名20岁及以上的人中就有一人患有高血压,只有39.64%的服药患者高血压得到良好控制。不同亚人群类别在负担和控制率方面存在显著差异。有针对性的干预措施有助于提高美国高血压的患病率和控制率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fa6/7803011/49c3f72ca629/gr1.jpg

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