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儿童 COVID-19 患者中的肺炎球菌携带情况。

Pneumococcal carriage in children with COVID-19.

机构信息

Department of Pediatric Infectious Diseases, University of Health Science Ankara Training and Research Hospital, Ankara, Turkey.

Department of Pediatric Infectious Diseases, Hacettepe University Faculty of Medicine, Ankara, Turkey.

出版信息

Hum Vaccin Immunother. 2021 Jun 3;17(6):1628-1634. doi: 10.1080/21645515.2020.1849516. Epub 2021 Jan 15.

Abstract

: SARS-CoV-2 is the new virus, and is one of the most important pathogens affecting humans. However, we do not yet know whether these microorganisms interact. Thus, we aimed to evaluate the relationship between and SARS-CoV-2 in pediatric patients.: This study was conducted retrospectively by means of medical records of pediatric patients who were tested for SARS-CoV-2 between March 11 and June 04, 2020, in the University of Health Sciences, Ankara Educating and Training Hospital and Hacettepe University Faculty of Medicine.: We evaluated 829 pediatric patients for and SARS-CoV-2 from their nasopharyngeal specimen. Of 115 children positive for SARS-CoV-2, 32.2% had a positive test, whereas of 714 children negative for SARS-CoV-2, 14.1% had a positive test ( < .01). We compared patients with positive vs. negative SARS-CoV-2 tests according to positivity There were no statistically significant differences in terms of gender, underlying disease, fever, cough, leukocytosis, lymphopenia, increased CRP, increased procalcitonin, findings of chest x-ray, severity of disease, and treatment.: The nasopharyngeal carriage rate in patients with COVID-19 was higher than in non-infected children, while carriage did not affect the course of COVID-19 disease. Pneumococcal vaccination is significant, such that we do not know the outcomes of increased pneumococcal carriage for the upcoming months of pandemic.

摘要

新型冠状病毒(SARS-CoV-2)是一种新出现的病毒,也是影响人类的最重要病原体之一。然而,我们尚不清楚这些微生物是否相互作用。因此,我们旨在评估小儿患者中 与 SARS-CoV-2 之间的关系。

本研究通过检索 2020 年 3 月 11 日至 6 月 04 日期间在安卡拉卫生科学大学、安卡拉教育和培训医院和哈塞特佩大学医学院接受 SARS-CoV-2 检测的儿科患者的病历进行回顾性研究。

我们从鼻咽拭子中评估了 829 名儿童的 SARS-CoV-2 和 。在 115 名 SARS-CoV-2 阳性的儿童中,32.2%的儿童 检测呈阳性,而在 714 名 SARS-CoV-2 阴性的儿童中,14.1%的儿童 检测呈阳性(<0.01)。我们根据 SARS-CoV-2 检测结果比较了阳性与阴性患者,在性别、基础疾病、发热、咳嗽、白细胞增多、淋巴细胞减少、CRP 升高、降钙素原升高、胸部 X 线检查结果、疾病严重程度和治疗方面均无统计学差异。

在 COVID-19 患者中,鼻咽 定植率高于未感染儿童,而 定植并不影响 COVID-19 疾病的病程。肺炎球菌疫苗接种意义重大,因此我们尚不清楚在未来几个月的大流行中,肺炎球菌定植增加的结果。

相似文献

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Pneumococcal carriage in children with COVID-19.儿童 COVID-19 患者中的肺炎球菌携带情况。
Hum Vaccin Immunother. 2021 Jun 3;17(6):1628-1634. doi: 10.1080/21645515.2020.1849516. Epub 2021 Jan 15.

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