Zalenski R J, Sloan E P, Chen E H, Hayden R F, Gold I W, Cooke D
Department of Surgery, University of Illinois, Chicago.
Ann Emerg Med. 1988 Mar;17(3):221-6. doi: 10.1016/s0196-0644(88)80110-0.
The emergency physician's disposition of patients with suspected myocardial ischemia is currently debated; some physicians believe that a subgroup of patients can be managed safely outside the coronary care unit. Clinical predictors are needed in assessing the patient with suspected myocardial ischemia to help identify this subgroup. Through a retrospective cohort study, we investigated the value of the initial emergency department ECG in discriminating between chest pain patients with low and high risk for immediately life-threatening complications. Two hundred eleven initially uncomplicated consecutive coronary care unit admissions with suspected unstable angina or myocardial infarction were studied. Patient outcome, including the incidence of myocardial infarction, complications, and mechanical and pharmacologic interventions, was reviewed. Immediately life-threatening complications included ventricular fibrillation, ventricular tachycardia, shock, 2 degrees and 3 degrees block, and death. Mechanical interventions included electrocardioversion or defibrillation, endotracheal intubation, intra-aortic balloon pump, Swan-Ganz catheter, or pacemaker insertion. Pressors, antiarrhythmics, and vasodilators were the reviewed pharmacologic interventions. A positive ECG was defined by the presence of ST elevation or depression, T wave inversion, left ventricular hypertrophy, left bundle branch block, paced rhythm, or new Q waves. All other ECG interpretations were considered negative. Patients were divided into two groups based on this initial emergency physician ECG interpretation and their complication incidences compared. Of the 211 patients, 96 had a positive ECG; 115 had negative ECGs. Patients with positive ECGs were older, had a greater history and concurrent incidence of myocardial infarction, and more complications and intensive interventions.(ABSTRACT TRUNCATED AT 250 WORDS)
目前,对于疑似心肌缺血患者的急诊处理存在争议;一些医生认为,部分患者可在冠心病监护病房之外安全地进行治疗。在评估疑似心肌缺血患者时,需要临床预测指标来帮助识别这一亚组患者。通过一项回顾性队列研究,我们调查了急诊科初始心电图在鉴别胸痛患者发生即刻危及生命并发症的低风险和高风险方面的价值。研究对象为211例最初无并发症、连续入住冠心病监护病房的疑似不稳定型心绞痛或心肌梗死患者。回顾了患者的结局,包括心肌梗死、并发症以及机械和药物干预的发生率。即刻危及生命的并发症包括心室颤动、室性心动过速、休克、二度和三度房室传导阻滞以及死亡。机械干预包括电复律或除颤、气管插管、主动脉内球囊反搏、 Swan-Ganz导管置入或起搏器植入。升压药、抗心律失常药和血管扩张剂为回顾的药物干预措施。心电图阳性定义为存在ST段抬高或压低、T波倒置、左心室肥厚、左束支传导阻滞、起搏心律或新出现的Q波。所有其他心电图解读均视为阴性。根据急诊科医生对初始心电图的解读将患者分为两组,并比较其并发症发生率。211例患者中,96例心电图阳性;115例心电图阴性。心电图阳性的患者年龄较大,有更多的心肌梗死病史和并发率,以及更多的并发症和强化干预措施。(摘要截短至250字)