Diffusiophoresis of a Highly Charged Soft Particle in Electrolyte Solutions.

Diffusiophoresis of a soft particle suspended in an infinite medium of symmetric binary electrolyte solution is investigated theoretically in this study, focusing on the chemiphoresis component when there is no global diffusion potential in the bulk solution. The general governing electrokinetic equations are solved with a pseudo-spectral method based on Chebyshev polynomials, and particle mobility, defined as the particle velocity per unit concentration gradient, is calculated. Parameters of electrokinetic interest are examined, in general, to explore their respective impact upon particle motion, such as the fixed charge density and permeability in the outer porous layer, the surface charge density and size of the inner rigid core, and the electrolyte strength in the solution. Nonlinear phenomena such as the motion-deterring double-layer polarization and the counterion condensation effects are scrutinized, in particular, for highly charged soft particles. Mobility reversal is observed in some range of electrolyte strength for highly charged particles. The generation of an axisymmetric counterclockwise vortex flow across the porous layer is found to be responsible for it. The onset of the mobility reversal is synchronized with the appearance or disappearance of this vortex flow. Mobility reversal may happen more than once, with particle moving toward or away from the region of higher solute concentration. The latter is undesirable in the application of drug delivery and thus should be avoided by delicate control of the electrokinetic environment. A local micro diffusion potential is discovered, which always speeds up the migration of coions and slows down that of counterions to guarantee that there is no net electric current across the double layer. Moreover, multilayer structure of the double-layer polarization is discovered when the electrolyte strength is high. The study presented here provides insight and crucial information for practical applications of soft particles, such as drug delivery.