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青少年复发性腮腺炎患儿腮腺唾液腺内镜检查的深度镇静

Deep Sedation for Pediatric Parotid Sialendoscopy in Juvenile Recurrent Parotitis.

作者信息

Capaccio Pasquale, Palermo Andrea, Lucchinelli Paolo, Marchesi Tiziana, Torretta Sara, Gaffuri Michele, Marchisio Paola, Pignataro Lorenzo

机构信息

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20100 Milan, Italy.

Department of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, 20100 Milan, Italy.

出版信息

J Clin Med. 2021 Jan 13;10(2):276. doi: 10.3390/jcm10020276.

Abstract

Sialendoscopy is a minimally invasive diagnostic and therapeutic tool for juvenile recurrent parotitis (JRP); the procedure is under general anesthesia, but local anesthesia has been used for sialendoscopy in children >8 years. Based on the experience in children with sedation for gastrointestinal endoscopy, we investigated the reliability and safety of deep sedation for sialendoscopy in JRP. Six children (3 females, 6-13 years) with episodes of parotid swelling underwent interventional (duct dilation and steroid irrigation) sialendoscopy with intravenous bolus of 1 mg/kg propofol and 1 mcg/kg fentanyl, and continuous infusion of 2 mg/kg/h propofol. Sialendoscopy under deep sedation was successfully performed in all the patients; the procedure was well tolerated, without any adverse effects. One event of full awakening was registered and promptly solved without needing to interrupt the procedure. Effectiveness of sialendoscopy under deep sedation was subjectively attested by high positive scores obtained at post-operative standardized questionnaires administered to the patients and their parents, and objectively by the lack of clinical recurrences during the follow-up. The combination of propofol and fentanyl seems to be a reliable and safe means of sedating children with JRP undergoing sialendoscopy.

摘要

涎腺内镜检查是一种用于儿童复发性腮腺炎(JRP)的微创诊断和治疗工具;该手术在全身麻醉下进行,但对于8岁以上儿童,涎腺内镜检查已采用局部麻醉。基于儿童胃肠内镜检查镇静的经验,我们研究了JRP患儿涎腺内镜检查深度镇静的可靠性和安全性。6名(3名女性,6 - 13岁)有腮腺肿胀发作的儿童接受了介入性(导管扩张和类固醇冲洗)涎腺内镜检查,静脉推注1 mg/kg丙泊酚和1 mcg/kg芬太尼,并持续输注2 mg/kg/h丙泊酚。所有患者均成功在深度镇静下完成涎腺内镜检查;该手术耐受性良好,无任何不良反应。记录到1次完全苏醒事件,无需中断手术即迅速解决。深度镇静下涎腺内镜检查的有效性通过对患者及其父母进行的术后标准化问卷调查获得的高阳性评分主观证实,并通过随访期间无临床复发客观证实。丙泊酚和芬太尼联合使用似乎是为接受涎腺内镜检查的JRP患儿进行镇静的可靠且安全的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1b9/7828661/9b8f6782e157/jcm-10-00276-g001.jpg

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