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唾液腺内镜在儿童复发性腮腺炎治疗中的应用——单中心经验

Sialendoscopy in Management of Juvenile Recurrent Parotitis-A Single Centre Experience.

作者信息

Pušnik Luka, Jerman Anže, Urbančič Jure, Aničin Aleksandar

机构信息

Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.

Department of Otorhinolaryngology and Cervicofacial Surgery, University Medical Center Ljubljana, 1000 Ljubljana, Slovenia.

出版信息

Children (Basel). 2022 Oct 27;9(11):1632. doi: 10.3390/children9111632.

Abstract

Juvenile recurrent parotitis is a rare inflammatory disease of the parotid gland that shares diverse therapeutic management between institutions. Sialendoscopy has been demonstrated as an efficient diagnostics and therapeutic method with minimal complications; however, due to the rarity of the disease and limited data, there is a lack of universal guidelines on its optimal management. Herein, we retrospectively analysed patients with juvenile recurrent parotitis who had the sialendoscopy performed at our tertiary centre. Descriptive data were retrieved along with the number of swelling episodes one year before and after the sialendoscopy intervention. In the last decade, twenty-nine sialendoscopic procedures were performed at our clinics on twenty-one patients diagnosed with juvenile recurrent parotitis. Most of them underwent the procedure under general anaesthesia (86%). In the year before and after the sialendoscopic procedure, the patients had 3.9 ± 2.7 and 0.2 ± 0.4 episodes of swelling per year, respectively. The difference proved to be statistically significant (p < 0.0001). The complete resolution was noted in sixteen patients (76%); however, the procedure was not repeated on the same side of any patient. Solely one patient had a relapse of the disease reported more than twelve months after the sialendoscopy, nonetheless, one of his exacerbation episodes was already reported in the first year after the sialendoscopy. The mean follow-up period of patients was 48.6 months (range, 13−116 months). All things considered, this study emphasises sialendoscopy as an effective minimally invasive diagnostic and therapeutic tool for the management of juvenile recurrent parotitis.

摘要

青少年复发性腮腺炎是一种罕见的腮腺炎症性疾病,各医疗机构对其治疗管理方式多样。唾液腺内镜检查已被证明是一种高效的诊断和治疗方法,并发症极少;然而,由于该疾病罕见且数据有限,目前缺乏关于其最佳管理的通用指南。在此,我们回顾性分析了在我们三级中心接受唾液腺内镜检查的青少年复发性腮腺炎患者。收集了描述性数据以及唾液腺内镜检查干预前后一年的肿胀发作次数。在过去十年中,我们诊所对21例诊断为青少年复发性腮腺炎的患者进行了29次唾液腺内镜检查。大多数患者在全身麻醉下接受该手术(86%)。在唾液腺内镜检查手术前后的一年中,患者每年的肿胀发作次数分别为3.9±2.7次和0.2±0.4次。差异具有统计学意义(p<0.0001)。16例患者(76%)实现了完全缓解;然而,没有任何患者在同一侧重复进行该手术。仅1例患者在唾液腺内镜检查后12个月以上报告疾病复发,尽管如此,他的一次加重发作在唾液腺内镜检查后的第一年就已报告。患者的平均随访期为48.6个月(范围为13 - 116个月)。综合考虑,本研究强调唾液腺内镜检查是治疗青少年复发性腮腺炎的一种有效的微创诊断和治疗工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3ba/9688286/9c2fc376f6e3/children-09-01632-g001.jpg

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