Unidad de Gestión Clínica de Radiodiagnóstico, Hospital Universitario Virgen del Rocío, Sevilla, España.
Unidad de Gestión Clínica de Radiodiagnóstico, Hospital Juan Ramón Jiménez, Huelva, España.
Radiologia (Engl Ed). 2021 Mar-Apr;63(2):159-169. doi: 10.1016/j.rx.2020.10.010. Epub 2021 Jan 13.
To review the pathophysiology of Fontan-associated liver disease, its histologic changes, and its radiologic manifestations.
Fontan-associated liver disease is the result of a set of structural and functional changes in the liver that occur secondary to hemodynamic changes brought about by Fontan surgery. The radiologic manifestations of Fontan-associated liver disease consist of changes in the size and shape of the liver, alterations in the signal intensity or pattern of enhancement, abnormalities in the vascular structures, and focal lesions, which include benign nodules with intense uptake in the arterial phase and hepatocellular carcinoma. Radiologists need to be familiar with this disease and its complications, because the number of patients who undergo Fontan surgery continues to increase, and these patients undergo an increasing number of imaging tests.
回顾法乐四联症相关肝疾病的病理生理学、组织学改变和放射学表现。
法乐四联症相关肝疾病是法乐四联症手术后血流动力学改变引起的一系列肝结构和功能变化的结果。法乐四联症相关肝疾病的放射学表现包括肝脏大小和形状的改变、信号强度或增强模式的改变、血管结构的异常以及局灶性病变,包括动脉期摄取明显增强的良性结节和肝细胞癌。放射科医生需要熟悉这种疾病及其并发症,因为接受法乐四联症手术的患者数量不断增加,这些患者接受的影像学检查也越来越多。