Téllez Luis, Rodríguez de Santiago Enrique, Albillos Agustín
Servicio de Gastroenterología y Hepatología, Hospital Universitario Ramón y Cajal, Universidad de Alcalá, Madrid, Spain.
Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
Rev Esp Cardiol (Engl Ed). 2018 Mar;71(3):192-202. doi: 10.1016/j.rec.2017.10.052. Epub 2018 Feb 9.
Fontan-associated liver disease refers to the disturbance in the liver secondary to hemodynamic changes and systemic venous congestion following Fontan surgery. Although the natural history of this disease has not yet been established, patients with more advanced liver injury develop the complications of portal hypertension, such as ascites, variceal haemorrhage, or encephalopathy. Moreover, patients with Fontan surgery may have an increased risk of hepatocellular carcinoma. Periodic liver monitoring is essential to prevent this disease and provide early treatment of liver complications.
Fontan相关肝病是指Fontan手术后继发于血流动力学改变和体循环静脉淤血的肝脏功能紊乱。尽管这种疾病的自然病程尚未明确，但肝损伤较严重的患者会出现门静脉高压的并发症，如腹水、静脉曲张出血或肝性脑病。此外，接受Fontan手术的患者患肝细胞癌的风险可能增加。定期进行肝脏监测对于预防这种疾病和早期治疗肝脏并发症至关重要。
