Division of Pediatric Nephrology, Hospital, Universitario Central de Asturias, Avda de Roma s/n, 33011, Oviedo, Asturias, Spain.
Department of Medicine, University of Oviedo, Oviedo, Asturias, Spain.
Calcif Tissue Int. 2021 Apr;108(4):423-438. doi: 10.1007/s00223-020-00787-z. Epub 2021 Jan 16.
This manuscript discusses mineral and bone disorders of chronic kidney disease (MBD-CKD) in pediatric patients with special emphasis on the underlying pathophysiology, the causes and clinical profile of growth retardation, the alterations in the growth plate, the strategies to optimize growth and the medical recommendations for prevention and treatment.
本手稿讨论了慢性肾脏病(CKD)患儿的矿物质和骨代谢紊乱(MBD-CKD),特别强调了潜在的病理生理学、生长迟缓的原因和临床特征、生长板的改变、优化生长的策略以及预防和治疗的医学建议。