Department of Chemistry & Biochemistry, Rowan University, Glassboro, NJ 08028, United States.
Department of Chemistry & Biochemistry, Rowan University, Glassboro, NJ 08028, United States.
J Chromatogr A. 2021 Feb 8;1638:461820. doi: 10.1016/j.chroma.2020.461820. Epub 2020 Dec 24.
In recent years, a trend toward utilizing open access resources for laboratory research has begun. Open-source design strategies for scientific hardware rely upon the use of widely available parts, especially those that can be directly printed using additive manufacturing techniques and electronic components that can be connected to low-cost microcontrollers. Open-source software eliminates the need for expensive commercial licenses and provides the opportunity to design programs for specific needs. In this review, the impact of the "open-source movement" within the field of chemical separations is described, primarily through a comprehensive look at research in this area over the past five years. Topics that are covered include general laboratory equipment, sample preparation techniques, separations-based analysis, detection strategies, electronic system control, and software for data processing. Remaining hurdles and possible opportunities for further adoption of open-source approaches in the context of these separations-related topics are also discussed.
近年来，利用开放获取资源进行实验室研究的趋势已经开始。科学硬件的开源设计策略依赖于广泛可用的部件的使用，特别是那些可以使用添加剂制造技术直接打印的部件和可以连接到低成本微控制器的电子元件。开源软件消除了对昂贵商业许可证的需求，并提供了为特定需求设计程序的机会。在这篇综述中，描述了“开源运动”在化学分离领域的影响，主要是通过全面回顾过去五年在该领域的研究。涵盖的主题包括一般实验室设备、样品制备技术、基于分离的分析、检测策略、电子系统控制以及数据处理软件。还讨论了在这些与分离相关的主题背景下，进一步采用开源方法的剩余障碍和可能的机会。
