在冷加压试验中，波强度（反映心室-动脉相互作用的指标）在高血压患者中增加，但在正常血压患者中降低。
Wave intensity, an index of ventriculo-arterial interaction, increases in hypertensive subjects but decreases in normotensive subjects during the cold pressor test.
机构信息
Faculty of Health Care Sciences, Himeji Dokkyo University, 7-2-1 Kamiohno, Himeji, Hyogo, Japan.
Faculty of Medicine, Tokyo Women's Medical University, Tokyo, Japan.
出版信息
J Med Ultrason (2001). 2021 Apr;48(2):199-203. doi: 10.1007/s10396-020-01077-9. Epub 2021 Jan 16.
PURPOSE
Cardiovascular reactivity to the cold pressor test (CPT) is considered to be a marker for apparent and potential hypertension. We aimed to elucidate the association between the changes in wave intensity (WI) during CPT and hypertension.
METHODS
We recruited 85 volunteers, 33 of whom were hypertensive and 52 normotensive. Using ultrasonic equipment during CPT, we measured carotid arterial WI, which is defined in terms of blood pressure and velocity in the carotid artery.
RESULTS
The peak WI (W) increased during CPT in 70.6% of hypertensive individuals, but decreased in 72.6% of normotensive individuals. The chi-square (χ) test showed that the association between the direction of change in W (increase or decrease) and the blood pressure (hypertensive or normotensive) was very strong (P < 0.0001).
CONCLUSION
Direction of change in W during CPT is a clear marker to discriminate cardiovascular reactivity that does not vary depending on each investigator's subjective point of view.
目的
冷加压试验（CPT）的心血管反应被认为是明显和潜在高血压的标志物。我们旨在阐明 CPT 期间波强（WI）变化与高血压之间的关系。
方法
我们招募了 85 名志愿者，其中 33 名患有高血压，52 名血压正常。在 CPT 期间使用超声设备，我们测量了颈动脉 WI，它是根据颈动脉中的血压和速度来定义的。
结果
70.6%的高血压患者在 CPT 期间 W 峰值增加，但 72.6%的血压正常患者 W 峰值下降。卡方（χ）检验表明，W 变化方向（增加或减少）与血压（高血压或血压正常）之间的关联非常强（P<0.0001）。
结论
CPT 期间 W 的变化方向是区分心血管反应的明确标志物，不受每个研究者主观观点的影响。
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