Behnamfar Fariba, Tashakor Zahra, Adibi Atoosa
Department of Obstetrics and Gynecology, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Radiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Biomed Res. 2020 Oct 30;9:64. doi: 10.4103/abr.abr_253_19. eCollection 2020.
The results of the former study confirmed the accuracy of magnetic resonance imaging (MRI) in determining the origin and content of ovarian masses. The present study aimed to evaluate the diagnostic value of MRI in differentiating benign and malignant ovarian masses in women.
This was a cross-sectional study. All candidates for surgery to remove ovarian masses were selected to participate in this study. They underwent MRI with gadolinium before the surgery. MRI images were reviewed by an experienced radiologist who was aware of the ovarian mass found in pelvic ultrasonography (US). A thick-enhancing wall, mural nodules, septations, and internal enhancement within the mass were reviewed by the radiologist. Mass specimens were examined in the laboratory by an experienced pathologist to determine malignancy or benignancy of the masses. Pathological findings were compared with MRI results.
there was no significant difference between MRI findings and pathology denoted by benign and malignant ( = 0.06), but results showed a significant difference between US and pathology ( = 0.002). In MRI findings related to a thick-enhancing wall ( = 0.18), internal enhancement ( = 0.18), and pelvic fluid ( = 1.00), no significant difference was seen in benign or malignant masses. However, in findings related to septation, all cases had malignant reports ( = 0.006), and in mural nodule, 80% had malignant reports ( = 0.006). CA-125 blood level in patients with benign masses (1.72 ± 0.97) was significantly less than patients with malignant masses (3.20 ± 0.83) ( < 0.001).
We showed that MRI has better results in diagnosing adnexal masses and their characteristics compared to simple ultrasound imaging based on pathological studies.
先前研究结果证实了磁共振成像（MRI）在确定卵巢肿块起源和内容物方面的准确性。本研究旨在评估MRI在鉴别女性卵巢良恶性肿块中的诊断价值。
这是一项横断面研究。所有计划进行卵巢肿块切除手术的患者均被选入本研究。她们在手术前接受了钆增强MRI检查。MRI图像由一位经验丰富的放射科医生进行评估，该医生知晓盆腔超声（US）检查发现的卵巢肿块情况。放射科医生对肿块内增厚强化的壁、壁结节、分隔及内部强化情况进行评估。肿块标本由一位经验丰富的病理学家在实验室进行检查，以确定肿块的良恶性。将病理结果与MRI结果进行比较。
MRI检查结果与病理诊断的良性和恶性之间无显著差异（P = 0.06），但结果显示US检查与病理结果之间存在显著差异（P = 0.002）。在与增厚强化壁（P = 0.18）、内部强化（P = 0.18）及盆腔积液（P = 1.00）相关的MRI检查结果中，良恶性肿块未见显著差异。然而，在与分隔相关的检查结果中，所有病例均为恶性报告（P = 0.006），在壁结节方面，80%为恶性报告（P = 0.006）。良性肿块患者的CA - 125血水平（1.72±0.97）显著低于恶性肿块患者（3.20±0.83）（P < 0.001）。
基于病理研究，我们发现与单纯超声成像相比，MRI在诊断附件肿块及其特征方面具有更好的结果。
