Sheckley Fahad, Nobert Craig, Stifelman Michael
Department of Urology, Hackensack University Medical Center, Hackensack, New Jersey, USA.
Department of Urology, Mount Sinai Health System, New York, New York, USA.
J Endourol Case Rep. 2020 Dec 29;6(4):536-539. doi: 10.1089/cren.2020.0180. eCollection 2020.
Renal cell carcinoma (RCC) originates from the renal parenchyma, whereas transitional cell carcinoma (TCC) originates from the renal urothelium. Although renal pelvis TCC is relatively rare in terms of urologic malignancies, it is the most common tumor originating in renal pelvis. A 75-year-old woman presented with gross hematuria found to have a filling defect in the renal pelvis with retrograde pyelogram and cytology showed clusters of urothelial cells, with imaging suspicious for TCC. Patient underwent robotic nephroureterectomy with partial cystectomy. Pathology analysis revealed RCC. RCC may occur in the renal pelvis mimicking TCC. Extensive preoperative evaluation to accurately diagnose tumor is key to avoid unnecessary procedures. Intraoperative pathologic evaluation is emphasized with inconclusive preoperative results.
肾细胞癌（RCC）起源于肾实质，而移行细胞癌（TCC）起源于肾尿路上皮。尽管肾盂TCC在泌尿系统恶性肿瘤中相对少见，但它是起源于肾盂的最常见肿瘤。一名75岁女性因肉眼血尿就诊，逆行肾盂造影显示肾盂有充盈缺损，细胞学检查发现尿路上皮细胞簇，影像学检查怀疑为TCC。患者接受了机器人辅助肾输尿管切除术及部分膀胱切除术。病理分析显示为RCC。RCC可能在肾盂发生，酷似TCC。进行全面的术前评估以准确诊断肿瘤是避免不必要手术的关键。术前结果不明确时，强调术中病理评估。
