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尼日利亚伊巴丹大学教学医院的腹壁子宫肌瘤切除术表现模式和并发症的临床审计。

A clinical audit of the patterns of presentations and complications of abdominal myomectomy at the University College Hospital, Ibadan, Nigeria.

机构信息

Department of Obstetrics and Gynaecology, University College Hospital, Ibadan, Nigeria.

Department of Obstetrics and Gynaecology, University College Hospital, University of Ibadan, Ibadan, Nigeria.

出版信息

J Obstet Gynaecol. 2021 Oct;41(7):1145-1150. doi: 10.1080/01443615.2020.1845632. Epub 2021 Jan 16.

Abstract

Abdominal myomectomy is a common modality of treatment for large and symptomatic uterine fibroids in women who wish to retain their fertility. Black women have higher rates and larger sizes of uterine fibroids. We aimed to determine the presentation patterns, peri-operative complications, and determinants of complications in patients who underwent abdominal myomectomy. This was a retrospective review of women who had abdominal myomectomy between July 2016 and June 2019. There were intra-operative complications and post-operative complications in 25% and 29.3% of patients respectively. There were higher odds for developing intra-operative complications among those who had general anaesthesia [OR = 3.514, 95%CI (1.951-6.331)], more than 10 fibroid nodules enucleated [OR = 4.917, 95%CI (2.600-9.298)], pre-operative Packed cell volume (PCV) < 30% [OR = 4.831, 95%CI (2.370-9.880)], presence of adhesions [OR = 2.680, 95%CI (1.510-4.730)], fibroids larger than 10 centimetres [OR = 1.98, 95%CI (1.13-3.49)], previous pelvic surgery [OR = 2.68, 95%CI (1.52-4.63)]. Post-operative complications were higher in those who had general anaesthesia or pre-existing medical conditions.IMPACT STATEMENT Abdominal myomectomy is a major surgical procedure globally with a significant morbidity rate. Sufficient evidence relating to the determinants of peri-operative complications are lacking. Our results highlight the factors associated with increased odds of developing complications following abdominal myomectomy. Our study complements existing data on the peri-operative complications following abdominal myomectomy. It also reflects the possibility of mortality albeit a rarerity. A retrospective multivariate analysis like this, while classifying morbidities into intra-operative and post-operative complications, is required to start an audit cycle. Knowing these determinants will help improve patient optimisation for surgery, identify high risk women and enhance more directed counselling. The results from this pilot study will also be used to design a prospective study to be undertaken by the authors.

摘要

腹部子宫肌瘤切除术是治疗希望保留生育能力的大型有症状子宫肌瘤的常见方法。黑人女性的子宫肌瘤发生率和肌瘤大小均较高。我们旨在确定接受腹部子宫肌瘤切除术患者的表现模式、围手术期并发症和并发症的决定因素。这是一项对 2016 年 7 月至 2019 年 6 月期间接受腹部子宫肌瘤切除术的女性进行的回顾性研究。分别有 25%和 29.3%的患者出现术中并发症和术后并发症。接受全身麻醉的患者发生术中并发症的可能性更高[比值比 (OR)=3.514,95%置信区间 (CI) (1.951-6.331)],切除的肌瘤结节超过 10 个[OR=4.917,95%CI (2.600-9.298)],术前红细胞压积(PCV)<30%[OR=4.831,95%CI (2.370-9.880)],有粘连[OR=2.680,95%CI (1.510-4.730)],肌瘤大于 10 厘米[OR=1.98,95%CI (1.13-3.49)],既往盆腔手术[OR=2.68,95%CI (1.52-4.63)]。接受全身麻醉或存在基础疾病的患者术后并发症发生率更高。

影响 腹部子宫肌瘤切除术是一种全球范围内的重大手术,其发病率较高。关于围手术期并发症决定因素的充分证据尚缺乏。我们的结果突出了与腹部子宫肌瘤切除术后并发症发生风险增加相关的因素。我们的研究补充了现有的关于腹部子宫肌瘤切除术后围手术期并发症的数据。它还反映了发生死亡的可能性,尽管这是一种罕见情况。像这样对围手术期并发症进行分类的回顾性多变量分析,需要开始一个审核周期。了解这些决定因素将有助于改善手术患者的优化,识别高危女性,并增强更有针对性的咨询。作者将使用这项初步研究的结果来设计一项前瞻性研究。

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