Joshi Hrishi, Sali Gaurav, Paramore Louise, Jones Richard, Lazarowicz Henry, Kujawa Magda Lucia, Pandit Amol, David Rotimi, Wilson Katherine, Bates Christopher, Shergill I, Gan Christine, El-Husseiny Tamer, Mukhtar Bashir, Appanna Timson, Veeratterapillay Rajan, Harding Christopher, Crockett Matthew, Dawson Christopher, Simpson Richard, Zelhof Bachar, Starmer B, Mukherjee Rono, Bourdoumis Andreas, Jelski Joseph, Hashim H, McCabe John, Shaw Greg, Chow Karyee, Betts Christopher
Consultant Urological Surgeon and Honorary lecturer, Department of Urology, University Hospital of Wales, UK.
Clinical Fellow in Urology, Department of Urology, University Hospital of Wales, UK.
Scott Med J. 2021 May;66(2):58-65. doi: 10.1177/0036933020977295. Epub 2021 Jan 17.
In view of changing landscape of surgical treatment for LUTS secondary to BPE, this audit was undertaken to assess key aspects of the processes and outcomes of the current interventional treatments for BPE, across different units in the UK.
A multi-institutional snapshot audit was conducted for patients undergoing interventions for LUTS/BPE over 8-week period. Using Delphi process two-part proforma was designed to capture data.
529 patients were included across 20 NHS trusts in England and Wales. Median age was 73 years. Indications for surgery were acute retention (47%) and LUTS (45%). 80% of patients had prior medical therapy. TURP formed the commonest procedure. 27% patients had <23 hour hospital stay. Immediate (21%) and delayed (18%) complications were Clavien-Dindo <2 category. High proportion of patients reported residual symptoms. Type and indication of surgery were significant predictor of complications, length of stay and failure of TWOC outcomes, on multivariate analyses. There were variations in departmental processes, 50% centres used PROMs.
Monopolar TURP still remains the commonest intervention for BPE. Most departments are adopting newer technologies. The audit identified opportunities for development of consistent, effective and patient centric practices as well as need for large-scale focused studies.
鉴于良性前列腺增生(BPE)继发下尿路症状(LUTS)的手术治疗格局不断变化,开展本次审核以评估英国不同单位当前BPE介入治疗的过程和结果的关键方面。
对在8周内接受LUTS/BPE干预治疗的患者进行多机构快照审核。采用德尔菲法设计了两部分的表格来收集数据。
英格兰和威尔士的20个国民保健服务信托机构纳入了529例患者。中位年龄为73岁。手术指征为急性尿潴留(47%)和LUTS(45%)。80%的患者曾接受过药物治疗。经尿道前列腺切除术(TURP)是最常见的手术。27%的患者住院时间<23小时。即刻(21%)和延迟(18%)并发症为Clavien-Dindo<2级。高比例患者报告有残余症状。多因素分析显示,手术类型和指征是并发症、住院时间和排尿后残余尿量(PVR)结果失败的重要预测因素。各部门的流程存在差异,50%的中心使用患者报告结局量表(PROMs)。
单极TURP仍然是BPE最常见的干预方式。大多数部门正在采用更新的技术。审核确定了发展一致有效且以患者为中心的实践的机会,以及开展大规模针对性研究的必要性。