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大脑前动脉远端破裂性动脉瘤蛛网膜下腔出血后胼胝体梗死所致无动性缄默症完全恢复。

Full recovery of Akinetic Mutism after corpus callosum infarction in post subarachnoid hemorrhage of ruptured distal anterior cerebral artery aneurysm.

机构信息

Division of Neurosurgery, Department of Surgery, College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia E-mail:

出版信息

Neurosciences (Riyadh). 2020 Oct;25(5):412-415. doi: 10.17712/nsj.2020.5.20200071.

DOI:10.17712/nsj.2020.5.20200071
PMID:33459293
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8015604/
Abstract

The authors report a previously healthy 23-year-old male patient who presented with subarachnoid hemorrhage and was found to have a ruptured right distal anterior cerebral artery aneurysm. He was treated by endovascular coiling technique, which was uneventful perioperatively. After a few days of mechanical ventilation and upon extubation, he expressed symptoms of apathy, drowsiness, lack of motivation, and lack of spontaneous motor function consistent with akinetic mutism. The magnetic resonance imaging of the brain revealed infarction of the whole body of corpus callosum. He remained in akinetic mutism status for twenty-one days before he started to show improvement until he fully recovered in 3 months. The authors report a unique finding where akinetic mutism resulted from infarction of the corpus callosum rather than medial frontal lobe (cingulate gyrus).

摘要

作者报告了一例既往健康的 23 岁男性患者,因蛛网膜下腔出血就诊,发现右侧大脑前动脉远端破裂性动脉瘤。患者接受了血管内弹簧圈栓塞治疗,手术过程顺利。几天后,患者在接受机械通气并拔管后出现冷漠、嗜睡、缺乏动力和自发性运动功能丧失等症状,符合无动性缄默症的表现。脑磁共振成像显示胼胝体体部梗死。患者持续无动性缄默状态 21 天后开始好转,3 个月后完全康复。作者报告了一个独特的发现,即无动性缄默症是由胼胝体梗死引起的,而不是内侧额叶(扣带回)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ad/8015604/2290d7927170/Neurosciences-25-412-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ad/8015604/20267e363f4a/Neurosciences-25-412-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ad/8015604/8f5ba95a9cfd/Neurosciences-25-412-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ad/8015604/349cda811e6b/Neurosciences-25-412-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ad/8015604/2290d7927170/Neurosciences-25-412-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ad/8015604/20267e363f4a/Neurosciences-25-412-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ad/8015604/8f5ba95a9cfd/Neurosciences-25-412-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ad/8015604/349cda811e6b/Neurosciences-25-412-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ad/8015604/2290d7927170/Neurosciences-25-412-g004.jpg

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Full recovery of Akinetic Mutism after corpus callosum infarction in post subarachnoid hemorrhage of ruptured distal anterior cerebral artery aneurysm.大脑前动脉远端破裂性动脉瘤蛛网膜下腔出血后胼胝体梗死所致无动性缄默症完全恢复。
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本文引用的文献

1
Reversible Akinetic Mutism after Aneurysmal Subarachnoid Haemorrhage in the Territory of the Anterior Cerebral Artery without Permanent Ischaemic Damage to Anterior Cingulate Gyri.大脑前动脉供血区动脉瘤性蛛网膜下腔出血后出现可逆性运动不能性缄默症,前扣带回无永久性缺血性损伤
Case Rep Neurol Med. 2016;2016:5193825. doi: 10.1155/2016/5193825. Epub 2016 Jun 23.
2
Subarachnoid haemorrhage and akinetic mutism.蛛网膜下腔出血与运动不能性缄默症。
Br J Neurosurg. 2004 Jun;18(3):253-8. doi: 10.1080/02688690410001732698.
3
Mutism in 36 patients who underwent callosotomy for drug-resistant epilepsy.
磁共振弥散张量成像纤维束示踪技术在评估无动性缄默症患者额皮质下环路中的作用的研究综述
Med Sci Monit. 2022 Feb 19;28:e936251. doi: 10.12659/MSM.936251.
36例因药物难治性癫痫接受胼胝体切开术患者的缄默症。
J Neurosurg Sci. 1997 Mar;41(1):93-6.
4
Mechanism of mutism following the transcallosal approach to the ventricles.经胼胝体入路至脑室后缄默症的机制。
Acta Neurochir (Wien). 1991;110(3-4):146-53. doi: 10.1007/BF01400683.