Department of Radiology, AZ Sint Jan Brugge-Oostende AV, Campus Sint Jan, Ruddershove 10, 8000, Bruges, Belgium.
Department of Radiology, University Hospitals Leuven, Leuven, Belgium.
Eur Radiol. 2021 Jul;31(7):4886-4897. doi: 10.1007/s00330-020-07392-6. Epub 2021 Jan 18.
The objective of this study is to report on the performance of the MRI-guided VABB in our center and to look at the long-term outcome of biopsies with benign histology over a period of 19 years.
In a single-center retrospective review study, data of 600 VABB procedures performed between September 1999 and March 2017 were evaluated. We collected patient demographics, histopathological diagnosis at MRI-VABB, and basic lesion characteristics (size, location). Data from the Belgian Cancer Registry was cross-referenced with our database to find out which patients with benign MRI-VABB results developed a malignant lesion over time.
These 600 VABB procedures were performed in 558 women with a mean patient age of 51.8 years (range 18-82 years). Our technical success rate was 99.3%. We found 27.67% B5 lesions, 9.82% B3 lesions, and 0.17% B4 lesions. Of 362 benign MRI-guided VABBs, follow-up data was available for a mean follow-up period of 7.6 years (0.8-18.3). Only one (0.3%) biopsy was a false negative lesion after MRI-guided VABB during follow-up. Short-term FU-MRI provided no increase in detection rate.
The accuracy of MRI-guided VABB is high with a very low false negative rate of 0.3% on long-term follow-up. The value of short-term FU-MRI for every case after MRI-guided VABB may be questioned.
• MRI-guided vacuum-assisted breast biopsies yield a large portion of clinically relevant lesions (9.82% B3, 0.17% B4, and 27.67% B5 lesions). • The false negative biopsy rate of MRI-guided VABB in this study with a mean follow-up time of 7.6 years was only 0.3%. • Performing a short-term follow-up MRI after a benign MRI-guided VABB concordant to the MRI appearance may be questioned.
本研究旨在报告我们中心 MRI 引导下 VABB 的性能，并观察 19 年来良性组织学活检的长期结果。
在一项单中心回顾性研究中，评估了 1999 年 9 月至 2017 年 3 月期间进行的 600 例 VABB 手术的数据。我们收集了患者的人口统计学数据、MRI-VABB 的组织病理学诊断以及基本病变特征（大小、位置）。通过与我们的数据库交叉引用比利时癌症登记处的数据，找出哪些 MRI-VABB 结果为良性的患者随着时间的推移发展出恶性病变。
这 600 例 VABB 手术在 558 名平均年龄为 51.8 岁（18-82 岁）的女性中进行。我们的技术成功率为 99.3%。我们发现 27.67%B5 病变、9.82%B3 病变和 0.17%B4 病变。在 362 例良性 MRI 引导下 VABB 中，平均随访时间为 7.6 年（0.8-18.3 年），有随访数据。在 MRI 引导下 VABB 后随访期间，仅 1 例（0.3%）活检为假阴性病变。短期 FU-MRI 并不能提高检出率。
MRI 引导下 VABB 的准确性很高，长期随访的假阴性率仅为 0.3%。对每个 MRI 引导下 VABB 后进行短期 FU-MRI 的价值可能需要进一步探讨。
MRI 引导下真空辅助乳房活检获得了很大一部分具有临床意义的病变（9.82%B3、0.17%B4 和 27.67%B5 病变）。
本研究中 MRI 引导下 VABB 的假阴性活检率在平均随访时间为 7.6 年的情况下仅为 0.3%。
在与 MRI 表现一致的情况下，对良性 MRI 引导下 VABB 进行短期随访 MRI 可能值得怀疑。
